Disease associated variation - ClinVar Allele ID Type Name RS#dbSNP Phenotype IDs Chromosome Start Stop Reference Alternate 222930 single nucleotide variant NM_005879.2(TRAIP):c.553C>T (p.Arg185Ter) 767664526 MedGen:CN235015,OMIM:616777 3 49841890 49841890 G A 222930 single nucleotide variant NM_005879.2(TRAIP):c.553C>T (p.Arg185Ter) 767664526 MedGen:CN235015,OMIM:616777 3 49879323 49879323 G A 222931 single nucleotide variant NM_005879.2(TRAIP):c.52C>T (p.Arg18Cys) 864622784 MedGen:CN235015,OMIM:616777 3 49893835 49893835 G A 222931 single nucleotide variant NM_005879.2(TRAIP):c.52C>T (p.Arg18Cys) 864622784 MedGen:CN235015,OMIM:616777 3 49856402 49856402 G A

Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 3 49869158 rs695238 A C rs695238 1.09E-05 Crohn's disease HPOID:0100280 DOID:8778 C intron GWASdb_trait 3 49878078 rs2271960 T C rs2271960 1.96E-05 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 3 49878113 rs2271961 T C rs2271961 5.62E-05 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 3 49878113 rs2271961 T C rs2271961 2.49E-06 Bipolar disorder, schizoaffective HPOID:0007302|HPOID:0100753 DOID:3312|DOID:5418 C intron GWASdb_trait 3 49882349 rs2247036 C T rs2247036 1.16E-05 Crohn's disease HPOID:0100280 DOID:8778 T intron GWASdb_trait 3 49890613 rs2352974 C T rs2352974 3.48E-05 Multiple complex diseases HPOID:0000118 NA T intron GWASdb_trait 3 49890613 rs2352974 C T rs2352974 2.02E-05 Crohn's disease HPOID:0100280 DOID:8778 T intron GWASdb_trait 3 49890613 rs2352974 C T rs2352974 8.27E-07 Bipolar disorder, schizoaffective HPOID:0007302|HPOID:0100753 DOID:3312|DOID:5418 T intron GWASdb_trait 3 49890613 rs2352974 C T rs2352974 0.000103 Height (Pygmy height) NA NA T intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000183763.8 TRAIP 605958