Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 6 33179042 33179042 + Nonsense_Mutation SNP C C G TCGA-ZF-AA58-01A-12D-A42E-08 TCGA-ZF-AA58-10A-01D-A42H-08 g.chr6:33179042C>G c.563C>G c.(562-564)tCa>tGa p.S188* BLCA 6 33179090 33179090 + Missense_Mutation SNP G G T TCGA-CU-A3QU-01A-11D-A22Z-08 TCGA-CU-A3QU-10B-01D-A22Z-08 g.chr6:33179090G>T c.611G>T c.(610-612)cGt>cTt p.R204L BLCA 6 33179194 33179194 + Silent SNP C C T TCGA-XF-A9T2-01A-11D-A42E-08 TCGA-XF-A9T2-10A-01D-A42H-08 g.chr6:33179194C>T c.715C>T c.(715-717)Ctg>Ttg p.L239L BLCA 6 33179769 33179769 + Missense_Mutation SNP G G T TCGA-K4-A5RJ-01A-11D-A289-08 TCGA-K4-A5RJ-10A-01D-A289-08 g.chr6:33179769G>T c.1109G>T c.(1108-1110)gGg>gTg p.G370V CESC 6 33180148 33180148 + Missense_Mutation SNP G G A TCGA-MU-A51Y-01A-11D-A26G-09 TCGA-MU-A51Y-10A-01D-A26G-09 g.chr6:33180148G>A c.1193G>A c.(1192-1194)tGc>tAc p.C398Y COAD 6 33176652 33176652 + Missense_Mutation SNP T T G TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chr6:33176652T>G c.53T>G c.(52-54)cTg>cGg p.L18R COAD 6 33177545 33177545 + Missense_Mutation SNP T T C TCGA-A6-6141-01A-11D-1771-10 TCGA-A6-6141-10A-01D-1771-10 g.chr6:33177545T>C c.221T>C c.(220-222)gTc>gCc p.V74A COAD 6 33178990 33178990 + Frame_Shift_Del DEL G G - TCGA-CK-6746-01A-11D-1835-10 TCGA-CK-6746-10A-01D-1835-10 g.chr6:33178990delG c.511delG c.(511-513)gggfs p.G172fs COAD 6 33178990 33178990 + Frame_Shift_Del DEL G G - TCGA-CM-4743-01A-01D-1719-10 TCGA-CM-4743-10A-01D-1719-10 g.chr6:33178990delG c.511delG c.(511-513)gggfs p.G172fs COAD 6 33178990 33178990 + Frame_Shift_Del DEL G G - TCGA-CM-6171-01A-11D-1650-10 TCGA-CM-6171-10A-01D-1650-10 g.chr6:33178990delG c.511delG c.(511-513)gggfs p.G172fs COAD 6 33179125 33179125 + Frame_Shift_Del DEL G G - TCGA-D5-6930-01A-11D-1924-10 TCGA-D5-6930-10A-01D-1924-10 g.chr6:33179125delG c.646delG c.(646-648)gggfs p.G219fs COAD 6 33179214 33179214 + Frame_Shift_Del DEL C C - TCGA-AA-3713-01A-21D-1719-10 TCGA-AA-3713-11A-01D-1719-10 g.chr6:33179214delC c.735delC c.(733-735)ggcfs p.G245fs COAD 6 33179214 33179214 + Frame_Shift_Del DEL C C - TCGA-CM-6171-01A-11D-1650-10 TCGA-CM-6171-10A-01D-1650-10 g.chr6:33179214delC c.735delC c.(733-735)ggcfs p.G245fs COAD 6 33179222 33179222 + Missense_Mutation SNP G G T TCGA-DM-A1HA-01A-11D-A152-10 TCGA-DM-A1HA-10A-01D-A152-10 g.chr6:33179222G>T c.743G>T c.(742-744)aGc>aTc p.S248I COAD 6 33179772 33179772 + Missense_Mutation SNP C C T TCGA-AA-3984-01A-02W-0995-10 TCGA-AA-3984-10A-01W-0999-10 g.chr6:33179772C>T c.1112C>T c.(1111-1113)gCg>gTg p.A371V COAD 6 33180076 33180076 + Splice_Site SNP C C T TCGA-G4-6586-01A-11D-1771-10 TCGA-G4-6586-10A-01D-1771-10 g.chr6:33180076C>T c.1121C>T c.(1120-1122)aCg>aTg p.T374M COADREAD 6 33176652 33176652 + Missense_Mutation SNP T T G TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chr6:33176652T>G c.53T>G c.(52-54)cTg>cGg p.L18R COADREAD 6 33177545 33177545 + Missense_Mutation SNP T T C TCGA-A6-6141-01A-11D-1771-10 TCGA-A6-6141-10A-01D-1771-10 g.chr6:33177545T>C c.221T>C c.(220-222)gTc>gCc p.V74A COADREAD 6 33177820 33177820 + Missense_Mutation SNP G G A TCGA-DC-5337-01A-01D-1657-10 TCGA-DC-5337-10A-01D-1657-10 g.chr6:33177820G>A c.368G>A c.(367-369)cGa>cAa p.R123Q COADREAD 6 33178990 33178990 + Frame_Shift_Del DEL G G - TCGA-CK-6746-01A-11D-1835-10 TCGA-CK-6746-10A-01D-1835-10 g.chr6:33178990delG c.511delG c.(511-513)gggfs p.G172fs COADREAD 6 33178990 33178990 + Frame_Shift_Del DEL G G - TCGA-CM-4743-01A-01D-1719-10 TCGA-CM-4743-10A-01D-1719-10 g.chr6:33178990delG c.511delG c.(511-513)gggfs p.G172fs COADREAD 6 33178990 33178990 + Frame_Shift_Del DEL G G - TCGA-CM-6171-01A-11D-1650-10 TCGA-CM-6171-10A-01D-1650-10 g.chr6:33178990delG c.511delG c.(511-513)gggfs p.G172fs COADREAD 6 33179125 33179125 + Frame_Shift_Del DEL G G - TCGA-D5-6930-01A-11D-1924-10 TCGA-D5-6930-10A-01D-1924-10 g.chr6:33179125delG c.646delG c.(646-648)gggfs p.G219fs COADREAD 6 33179214 33179214 + Frame_Shift_Del DEL C C - TCGA-AA-3713-01A-21D-1719-10 TCGA-AA-3713-11A-01D-1719-10 g.chr6:33179214delC c.735delC c.(733-735)ggcfs p.G245fs COADREAD 6 33179214 33179214 + Frame_Shift_Del DEL C C - TCGA-CM-6171-01A-11D-1650-10 TCGA-CM-6171-10A-01D-1650-10 g.chr6:33179214delC c.735delC c.(733-735)ggcfs p.G245fs COADREAD 6 33179222 33179222 + Missense_Mutation SNP G G T TCGA-DM-A1HA-01A-11D-A152-10 TCGA-DM-A1HA-10A-01D-A152-10 g.chr6:33179222G>T c.743G>T c.(742-744)aGc>aTc p.S248I COADREAD 6 33179772 33179772 + Missense_Mutation SNP C C T TCGA-AA-3984-01A-02W-0995-10 TCGA-AA-3984-10A-01W-0999-10 g.chr6:33179772C>T c.1112C>T c.(1111-1113)gCg>gTg p.A371V COADREAD 6 33180076 33180076 + Splice_Site SNP C C T TCGA-G4-6586-01A-11D-1771-10 TCGA-G4-6586-10A-01D-1771-10 g.chr6:33180076C>T c.1121C>T c.(1120-1122)aCg>aTg p.T374M ESCA 6 33177715 33177715 + Missense_Mutation SNP G G T TCGA-2H-A9GL-01A-12D-A37C-09 TCGA-2H-A9GL-11A-11D-A37F-09 g.chr6:33177715G>T c.263G>T c.(262-264)cGa>cTa p.R88L GBMLGG 6 33178997 33178997 + Missense_Mutation SNP A A G TCGA-CS-6668-01A-11D-1893-08 TCGA-CS-6668-10A-01D-1893-08 g.chr6:33178997A>G c.518A>G c.(517-519)gAa>gGa p.E173G HNSC 6 33176605 33176605 + Silent SNP G G A TCGA-UF-A7JO-01A-11D-A34J-08 TCGA-UF-A7JO-10A-01D-A34M-08 g.chr6:33176605G>A c.6G>A c.(4-6)acG>acA p.T2T HNSC 6 33177826 33177826 + Missense_Mutation SNP T T G TCGA-CN-4725-01A-01D-1434-08 TCGA-CN-4725-10A-01D-1434-08 g.chr6:33177826T>G c.374T>G c.(373-375)cTt>cGt p.L125R HNSC 6 33179753 33179753 + Missense_Mutation SNP A A T TCGA-WA-A7GZ-01A-11D-A34J-08 TCGA-WA-A7GZ-10A-01D-A34M-08 g.chr6:33179753A>T c.1093A>T c.(1093-1095)Atc>Ttc p.I365F HNSC 6 33180132 33180132 + Missense_Mutation SNP C C T TCGA-DQ-7588-01A-11D-2078-08 TCGA-DQ-7588-10B-01D-2078-08 g.chr6:33180132C>T c.1177C>T c.(1177-1179)Cgg>Tgg p.R393W KICH 6 33179664 33179664 + Missense_Mutation SNP A A G TCGA-KL-8343-01A-11D-2310-10 TCGA-KL-8343-11A-01D-2310-10 g.chr6:33179664A>G c.1004A>G c.(1003-1005)gAg>gGg p.E335G KIPAN 6 33179580 33179580 + Missense_Mutation SNP G G A TCGA-A4-A772-01A-11D-A33Q-10 TCGA-A4-A772-10A-01D-A33Q-10 g.chr6:33179580G>A c.920G>A c.(919-921)cGg>cAg p.R307Q KIPAN 6 33179664 33179664 + Missense_Mutation SNP A A G TCGA-KL-8343-01A-11D-2310-10 TCGA-KL-8343-11A-01D-2310-10 g.chr6:33179664A>G c.1004A>G c.(1003-1005)gAg>gGg p.E335G KIPAN 6 33180123 33180123 + Frame_Shift_Del DEL A A - TCGA-B8-5165-01A-01D-1421-08 TCGA-B8-5165-10A-01D-1421-08 g.chr6:33180123delA c.1168delA c.(1168-1170)aagfs p.K390fs KIRC 6 33180123 33180123 + Frame_Shift_Del DEL A A - TCGA-B8-5165-01A-01D-1421-08 TCGA-B8-5165-10A-01D-1421-08 g.chr6:33180123delA c.1168delA c.(1168-1170)aagfs p.K390fs KIRP 6 33179580 33179580 + Missense_Mutation SNP G G A TCGA-A4-A772-01A-11D-A33Q-10 TCGA-A4-A772-10A-01D-A33Q-10 g.chr6:33179580G>A c.920G>A c.(919-921)cGg>cAg p.R307Q LGG 6 33178997 33178997 + Missense_Mutation SNP A A G TCGA-CS-6668-01A-11D-1893-08 TCGA-CS-6668-10A-01D-1893-08 g.chr6:33178997A>G c.518A>G c.(517-519)gAa>gGa p.E173G LIHC 6 33177781 33177781 + Missense_Mutation SNP T T G TCGA-BC-A112-01A-11D-A12Z-10 TCGA-BC-A112-11A-11D-A12Z-10 g.chr6:33177781T>G c.329T>G c.(328-330)aTc>aGc p.I110S LIHC 6 33180112 33180112 + Missense_Mutation SNP A A G TCGA-G3-A3CJ-01A-11D-A20W-10 TCGA-G3-A3CJ-10A-01D-A20W-10 g.chr6:33180112A>G c.1157A>G c.(1156-1158)gAg>gGg p.E386G LUAD 6 33177712 33177712 + Missense_Mutation SNP G G T TCGA-55-A4DG-01A-11D-A24D-08 TCGA-55-A4DG-10A-01D-A24F-08 g.chr6:33177712G>T c.260G>T c.(259-261)tGc>tTc p.C87F LUAD 6 33177789 33177789 + Missense_Mutation SNP A A G TCGA-86-8358-01A-11D-2323-08 TCGA-86-8358-10A-01D-2323-08 g.chr6:33177789A>G c.337A>G c.(337-339)Agc>Ggc p.S113G LUAD 6 33179100 33179100 + Silent SNP C C T TCGA-86-A4JF-01A-11D-A24P-08 TCGA-86-A4JF-10A-01D-A24P-08 g.chr6:33179100C>T c.621C>T c.(619-621)ggC>ggT p.G207G LUAD 6 33179254 33179254 + Missense_Mutation SNP G G T TCGA-95-7039-01A-11D-1945-08 TCGA-95-7039-10A-01D-1946-08 g.chr6:33179254G>T c.775G>T c.(775-777)Ggt>Tgt p.G259C LUAD 6 33179586 33179586 + Missense_Mutation SNP A A G TCGA-53-A4EZ-01A-12D-A24P-08 TCGA-53-A4EZ-10A-01D-A24P-08 g.chr6:33179586A>G c.926A>G c.(925-927)cAa>cGa p.Q309R LUAD 6 33179629 33179629 + Silent SNP C C T TCGA-55-7570-01A-11D-2036-08 TCGA-55-7570-10A-01D-2036-08 g.chr6:33179629C>T c.969C>T c.(967-969)gcC>gcT p.A323A LUSC 6 33179274 33179274 + Silent SNP G G C TCGA-39-5031-01A-01D-1441-08 TCGA-39-5031-11A-01D-1441-08 g.chr6:33179274G>C c.795G>C c.(793-795)gtG>gtC p.V265V LUSC 6 33179559 33179559 + Missense_Mutation SNP C C G TCGA-66-2782-01A-01D-1522-08 TCGA-66-2782-11A-01D-1522-08 g.chr6:33179559C>G c.899C>G c.(898-900)gCc>gGc p.A300G OV 6 33177781 33177781 + Missense_Mutation SNP T T G TCGA-04-1347-01A-01W-0488-09 TCGA-04-1347-11A-01W-0489-09 g.chr6:33177781T>G c.329T>G c.(328-330)aTc>aGc p.I110S PAAD 6 33179292 33179292 + Silent SNP G G A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr6:33179292G>A c.813G>A c.(811-813)ctG>ctA p.L271L PAAD 6 33179615 33179615 + Missense_Mutation SNP C C T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr6:33179615C>T c.955C>T c.(955-957)Cct>Tct p.P319S PAAD 6 33180151 33180151 + Missense_Mutation SNP A A G TCGA-FZ-5922-01A-11D-1609-08 TCGA-FZ-5922-11A-01D-1609-08 g.chr6:33180151A>G c.1196A>G c.(1195-1197)tAt>tGt p.Y399C PRAD 6 33177793 33177793 + Missense_Mutation SNP G G A TCGA-HC-8257-01A-11D-2260-08 TCGA-HC-8257-10A-01D-2260-08 g.chr6:33177793G>A c.341G>A c.(340-342)cGg>cAg p.R114Q PRAD 6 33177832 33177832 + Missense_Mutation SNP G G A TCGA-KK-A59V-01A-11D-A29Q-08 TCGA-KK-A59V-11A-11D-A29Q-08 g.chr6:33177832G>A c.380G>A c.(379-381)cGc>cAc p.R127H READ 6 33177820 33177820 + Missense_Mutation SNP G G A TCGA-DC-5337-01A-01D-1657-10 TCGA-DC-5337-10A-01D-1657-10 g.chr6:33177820G>A c.368G>A c.(367-369)cGa>cAa p.R123Q SARC 6 33177437 33177437 + Missense_Mutation SNP C C T TCGA-DX-AB2E-01A-11D-A38Z-09 TCGA-DX-AB2E-10A-01D-A38Z-09 g.chr6:33177437C>T c.113C>T c.(112-114)tCc>tTc p.S38F SKCM 6 33177517 33177517 + Missense_Mutation SNP C C T TCGA-ER-A198-06A-11D-A196-08 TCGA-ER-A198-10A-01D-A198-08 g.chr6:33177517C>T c.193C>T c.(193-195)Ctc>Ttc p.L65F SKCM 6 33177794 33177794 + Silent SNP G G A TCGA-EE-A2GB-06A-11D-A197-08 TCGA-EE-A2GB-10A-01D-A199-08 g.chr6:33177794G>A c.342G>A c.(340-342)cgG>cgA p.R114R SKCM 6 33178988 33178988 + Missense_Mutation SNP G G T TCGA-FS-A1ZW-06A-12D-A197-08 TCGA-FS-A1ZW-10A-01D-A199-08 g.chr6:33178988G>T c.509G>T c.(508-510)aGt>aTt p.S170I SKCM 6 33179271 33179271 + Silent SNP C C T TCGA-EE-A29D-06A-11D-A197-08 TCGA-EE-A29D-10A-01D-A199-08 g.chr6:33179271C>T c.792C>T c.(790-792)ctC>ctT p.L264L

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-BR-6452-01 COSM3873107 c.119G>A p.R40Q Substitution - Missense 6:33209666-33209666 + P03-1334 COSM247046 c.777T>G p.G259G Substitution - coding silent 6:33211479-33211479 + PTC-70C COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + HCT15 COSM4625770 c.1065C>T p.G355G Substitution - coding silent 6:33211948-33211948 + DN1401F COSM5960880 c.1158G>C p.E386D Substitution - Missense 6:33212336-33212336 + CSCC-45-T COSM4472876 c.180C>T p.T60T Substitution - coding silent 6:33209727-33209727 + TCGA-B7-5816-01 COSM3873112 c.869C>T p.A290V Substitution - Missense 6:33211752-33211752 + TCGA-CG-5721-01 COSM3873108 c.238G>A p.G80R Substitution - Missense 6:33209785-33209785 + LS180 COSM4646143 c.545A>G p.D182G Substitution - Missense 6:33211247-33211247 + pfg129T COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + TCGA-CU-A3QU-01 COSM3777560 c.611G>T p.R204L Substitution - Missense 6:33211313-33211313 + LS180 COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + TCGA-HU-A4GX-01 COSM3873111 c.621C>T p.G207G Substitution - coding silent 6:33211323-33211323 + TCGA-AA-3713-01 COSM1443749 c.735delC p.P247fs*38 Deletion - Frameshift 6:33211437-33211437 + CHC051T COSM3669590 c.1107C>A p.G369G Substitution - coding silent 6:33211990-33211990 + TCGA-BC-A112-01 COSM76238 c.329T>G p.I110S Substitution - Missense 6:33210004-33210004 + LS174T COSM4646143 c.545A>G p.D182G Substitution - Missense 6:33211247-33211247 + TCGA-MU-A51Y-01 COSM4836501 c.1193G>A p.C398Y Substitution - Missense 6:33212371-33212371 + WSU-HN12 COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + ME011T COSM224300 c.641G>A p.G214E Substitution - Missense 6:33211343-33211343 + TCGA-13-0751-01 COSM116479 c.593C>T p.P198L Substitution - Missense 6:33211295-33211295 + 1_RESISTANT COSM1720270 c.877G>A p.D293N Substitution - Missense 6:33211760-33211760 + TCGA-D1-A174-01 COSM1077972 c.1055G>A p.S352N Substitution - Missense 6:33211938-33211938 + HCA7 COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + UM-SCC-2 COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + LOVO COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + Pat_36_B COSM4613683 c.510_511insG p.E173fs*21 Insertion - Frameshift 6:33211212-33211213 + 93VU147T COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + Detroit_562 COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + NB-1613 COSM1287634 c.1166G>A p.W389* Substitution - Nonsense 6:33212344-33212344 + RK198_C01 COSM3745189 c.175A>G p.M59V Substitution - Missense 6:33209722-33209722 + TCGA-ER-A198-06 COSM3625667 c.193C>T p.L65F Substitution - Missense 6:33209740-33209740 + TCGA-04-1347-01 COSM76238 c.329T>G p.I110S Substitution - Missense 6:33210004-33210004 + cSCCP4 COSM138552 c.301C>T p.P101S Substitution - Missense 6:33209976-33209976 + TCGA-CM-4743-01 COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + TCGA-D1-A17Q-01 COSM1077965 c.234G>A p.R78R Substitution - coding silent 6:33209781-33209781 + TCGA-BG-A0M0-01 COSM1077967 c.284G>A p.R95Q Substitution - Missense 6:33209959-33209959 + LP6005409-DNA_F02 COSM4408754 c.209C>T p.S70F Substitution - Missense 6:33209756-33209756 + Pat_63_B COSM5870367 c.977C>T p.T326I Substitution - Missense 6:33211860-33211860 + SCC-9 COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + TCGA-CD-5802-01 COSM1077967 c.284G>A p.R95Q Substitution - Missense 6:33209959-33209959 + NOKSI COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + TCGA-G4-6586-01 COSM1443751 c.1121C>T p.T374M Substitution - Missense 6:33212299-33212299 + tumor_4128852 COSM5948506 c.141G>A p.M47I Substitution - Missense 6:33209688-33209688 + LIM2405 COSM1077968 c.436C>T p.R146C Substitution - Missense 6:33210111-33210111 + HCT8 COSM4625770 c.1065C>T p.G355G Substitution - coding silent 6:33211948-33211948 + TCGA-BR-8487-01 COSM3873110 c.570C>T p.S190S Substitution - coding silent 6:33211272-33211272 + 1_PRE-TREATMENT COSM1720270 c.877G>A p.D293N Substitution - Missense 6:33211760-33211760 + PR-00-1165 COSM247045 c.313G>A p.A105T Substitution - Missense 6:33209988-33209988 + TCGA-DC-5337-01 COSM1568400 c.368G>A p.R123Q Substitution - Missense 6:33210043-33210043 + TCGA-HC-8257-01 COSM4393718 c.341G>A p.R114Q Substitution - Missense 6:33210016-33210016 + TCGA-D1-A103-01 COSM1077971 c.1017C>T p.A339A Substitution - coding silent 6:33211900-33211900 + LS411 COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + TCGA-AP-A0LP-01 COSM1077966 c.238G>T p.G80W Substitution - Missense 6:33209785-33209785 + T2197 COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + WSU-HN8 COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + SCC-25 COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + C058 COSM5525525 c.261C>T p.C87C Substitution - coding silent 6:33209936-33209936 + CHC1489T COSM3669521 c.394C>T p.H132Y Substitution - Missense 6:33210069-33210069 + AOCS-114-1-8 COSM4153292 c.745C>T p.P249S Substitution - Missense 6:33211447-33211447 + PTC-53C COSM4161064 c.583G>A p.A195T Substitution - Missense 6:33211285-33211285 + DLD1 COSM4625770 c.1065C>T p.G355G Substitution - coding silent 6:33211948-33211948 + pfg212T COSM4752387 c.314C>T p.A105V Substitution - Missense 6:33209989-33209989 + LS174T COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + Gp2D COSM3349517 c.984A>C p.G328G Substitution - coding silent 6:33211867-33211867 + CAL27 COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + cSCCP4 COSM138553 c.406G>A p.A136T Substitution - Missense 6:33210081-33210081 + CHC051T COSM3669590 c.1107C>A p.G369G Substitution - coding silent 6:33211990-33211990 + BICR_22 COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + CSCC-31-T COSM4507521 c.748C>T p.P250S Substitution - Missense 6:33211450-33211450 + C037 COSM5524472 c.1176C>T p.S392S Substitution - coding silent 6:33212354-33212354 + TCGA-KK-A59V-01 COSM4878497 c.380G>A p.R127H Substitution - Missense 6:33210055-33210055 + TCGA-AM-5820-01 COSM3761990 c.1029C>T p.D343D Substitution - coding silent 6:33211912-33211912 + TCGA-DM-A1HA-01 COSM1443750 c.743G>T p.S248I Substitution - Missense 6:33211445-33211445 + TCGA-EE-A2GB-06 COSM3625668 c.342G>A p.R114R Substitution - coding silent 6:33210017-33210017 + TCGA-AP-A05A-01 COSM1077969 c.501A>C p.T167T Substitution - coding silent 6:33211203-33211203 + Gp5D COSM3349517 c.984A>C p.G328G Substitution - coding silent 6:33211867-33211867 + MZ7-mel COSM27223 c.933G>A p.Q311Q Substitution - coding silent 6:33211816-33211816 + TCGA-39-5031-01 COSM742365 c.795G>C p.V265V Substitution - coding silent 6:33211497-33211497 + TCGA-AX-A0J1-01 COSM1077970 c.898G>A p.A300T Substitution - Missense 6:33211781-33211781 + Detroit_562 COSM4595317 c.1014T>G p.G338G Substitution - coding silent 6:33211897-33211897 + 107T COSM1237920 c.293G>A p.R98Q Substitution - Missense 6:33209968-33209968 + C058 COSM5525524 c.262C>T p.R88* Substitution - Nonsense 6:33209937-33209937 + TCGA-D1-A176-01 COSM1077968 c.436C>T p.R146C Substitution - Missense 6:33210111-33210111 + CSCC-32-T COSM4519600 c.1019G>A p.G340E Substitution - Missense 6:33211902-33211902 + SNU-175 COSM1443746 c.221T>C p.V74A Substitution - Missense 6:33209768-33209768 + I2L-P20-Tumor-Biopsy COSM5357478 c.516G>T p.G172G Substitution - coding silent 6:33211218-33211218 + T3090 COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + TCGA-EE-A29D-06 COSM3625670 c.792C>T p.L264L Substitution - coding silent 6:33211494-33211494 + CAL33 COSM451292 c.1004A>G p.E335G Substitution - Missense 6:33211887-33211887 + TCGA-D5-6930-01 COSM1443748 c.646delG p.G217fs*68 Deletion - Frameshift 6:33211348-33211348 + TCGA-66-2782-01 COSM742364 c.899C>G p.A300G Substitution - Missense 6:33211782-33211782 + LIM2405 COSM4613683 c.510_511insG p.E173fs*21 Insertion - Frameshift 6:33211212-33211213 + LS174T COSM3349519 c.998G>A p.G333D Substitution - Missense 6:33211881-33211881 + TCGA-A6-6141-01 COSM1443746 c.221T>C p.V74A Substitution - Missense 6:33209768-33209768 + T3503 COSM3873108 c.238G>A p.G80R Substitution - Missense 6:33209785-33209785 + H2171 COSM314818 c.512G>T p.G171V Substitution - Missense 6:33211214-33211214 + ESO-075 COSM1264294 c.263G>T p.R88L Substitution - Missense 6:33209938-33209938 + RK126_C01 COSM1634750 c.1169A>C p.K390T Substitution - Missense 6:33212347-33212347 + TCGA-DD-A11C-01 COSM4925562 c.482C>T p.P161L Substitution - Missense 6:33211184-33211184 + LS180 COSM3349519 c.998G>A p.G333D Substitution - Missense 6:33211881-33211881 + TCGA-CM-6171-01 COSM1443747 c.511delG p.E173fs*14 Deletion - Frameshift 6:33211213-33211213 + C135 COSM4611188 c.755delC p.S254fs*31 Deletion - Frameshift 6:33211457-33211457 + TCGA-CM-6171-01 COSM1443749 c.735delC p.P247fs*38 Deletion - Frameshift 6:33211437-33211437 + TCGA-FS-A1ZW-06 COSM3625669 c.509G>T p.S170I Substitution - Missense 6:33211211-33211211 + TCGA-BR-4368-01 COSM3873109 c.517G>A p.E173K Substitution - Missense 6:33211219-33211219 + 18 COSM5744880 c.842C>T p.T281M Substitution - Missense 6:33211544-33211544 + Detroit_562 COSM4595316 c.1008T>G p.G336G Substitution - coding silent 6:33211891-33211891 + PTC-6C COSM4161065 c.615A>G p.G205G Substitution - coding silent 6:33211317-33211317 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.631989 6p21.3 602045

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Missense p.K390T c.1169A>C 6 33180124 HC A C Synonymous p.T167T c.501A>C 6 33178980 UCEC A - Frameshift p.K390Rfs*175 c.1169delA 6 33180123 RCCC A G Missense p.E173G c.518A>G 6 33178997 CM C A Synonymous p.P176P c.528C>A 6 33179007 CM C G Missense p.A300G c.899C>G 6 33179559 LUSC C G Missense p.Q154E c.460C>G 6 33178939 CM C T Missense p.A290V c.869C>T 6 33179529 STAD C T Missense p.L65F c.193C>T 6 33177517 CM C T Missense p.P198L c.593C>T 6 33179072 OV C T Missense p.P200S c.598C>T 6 33179077 CM C T Missense p.R393W c.1177C>T 6 33180132 HNSC C T Synonymous p.A252A c.756C>T 6 33179235 CM C T Synonymous p.T166T c.498C>T 6 33178977 CM G A Missense p.E173K c.517G>A 6 33178996 STAD G A Missense p.R114Q c.341G>A 6 33177793 PRAD G A Missense p.R95Q c.284G>A 6 33177736 STAD G A Missense p.R95Q c.284G>A 6 33177736 UCEC G A Missense p.S352N c.1055G>A 6 33179715 UCEC G A Nonsense p.W389* c.1166G>A 6 33180121 NB G A Synonymous p.Q165Q c.495G>A 6 33178974 CM G A Synonymous p.R114R c.342G>A 6 33177794 CM G C Synonymous p.V265V c.795G>C 6 33179274 LUSC G T Missense p.R88L c.263G>T 6 33177715 ESCA G T Missense p.S170I c.509G>T 6 33178988 CM T G Missense p.I110S c.329T>G 6 33177781 OV T G Missense p.L125R c.374T>G 6 33177826 HNSC