DNA & RNA Element - AREsite Gene Name Motif CDS Area ARE Area Evidence Sqstm1; A170; STAP ATTTA 35-1249 2365-2369

DNA & RNA Element - miRTarBase Target Gene (Entrez ID) miRTarBase ID miRNA Species (miRNA) Target Gene Species (Target Gene) Experiments Support Type References (PMID) MIRT006739 mmu-miR-106a-5p Mus musculus Sqstm1 18412 Mus musculus FACS//Luciferase reporter assay//qRT-PCR//Western blot Functional MTI 21628417 MIRT006737 mmu-miR-20a-5p Mus musculus Sqstm1 18412 Mus musculus FACS//Luciferase reporter assay//qRT-PCR//Western blot Functional MTI 21628417 MIRT006738 mmu-miR-93-5p Mus musculus Sqstm1 18412 Mus musculus FACS//Luciferase reporter assay//qRT-PCR//Western blot Functional MTI 21628417 MIRT006736 mmu-miR-17-5p Mus musculus Sqstm1 18412 Mus musculus FACS//Luciferase reporter assay//qRT-PCR//Western blot Functional MTI 21628417

DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0004529 mmu-miR-125b* 18412 Sqstm1 uccaggguucuuGGACUGAACa :|||||||| cauguagcuuccUCUGACUUGg 2 11 574 595 [mm9:11:50013697-50013718:-] 0.5099 146 7 -17.07 -0.2691 MIMAT0004546 mmu-miR-202-5p 18412 Sqstm1 uuUCUUCAUAUACGUA-UCCUu | |:| | :||||| |||| caAUAGGAAAGUGCAUGAGGAg 2 20 135 156 [mm9:11:50014136-50014157:-] 0.4980 127 0 -14.72 -0.5292 MIMAT0004546 mmu-miR-202-5p 18412 Sqstm1 uuUCUUCAUAUACGUAUC-CUu ||::| |:| ||||| || agAGGGGACUGUCCAUAGUGAg 2 20 403 424 [mm9:11:50013868-50013889:-] 0.4649 123 0 -14.85 -0.1512 MIMAT0000376 mmu-miR-298 18412 Sqstm1 cccuuCUUGUC-GGGAGGAGACGg ||:| | |:|||||||| uggcuGAGCUGAGCUUCCUCUGCu 2 19 206 229 [mm9:11:50014063-50014086:-] 0.4744 157 7 -27.78 -0.1736 MIMAT0000376 mmu-miR-298 18412 Sqstm1 cccuucuuGUCGGGA--GGAGACGg :|| ||| ||||||| gcuuucccUAGGCCUGGCCUCUGCa 2 16 227 251 [mm9:11:50014041-50014065:-] 0.4744 150 7 -21.43 -0.1008 MIMAT0004630 mmu-miR-26b* 18412 Sqstm1 cuCGGUUCAUUACCUCUUGUCc ||::| | |||||||| auGCUGACGCCU-GAGAACAGa 2 21 173 193 [mm9:11:50014099-50014119:-] 0.4744 146 7 -13.88 -0.2277 MIMAT0004634 mmu-miR-31* 18412 Sqstm1 cuacCGUUAUACAACCGUAU-CGu |:|||| ||||||| || accuGUAAUAAAAUGGCAUAUGCa 2 20 606 629 [mm9:11:50013663-50013686:-] 0.5099 131 0 -17.17 -0.5727 MIMAT0004635 mmu-miR-92a* 18412 Sqstm1 cauuACGGUGGUUAGGGGUGGa ||: :|||| ||||||| gugcUGUGGCCAAGCCCCACCc 2 19 3 24 [mm9:11:50014268-50014289:-] 0.3067 166 7 -28.00 -0.1119 MIMAT0000569 mmu-miR-330* 18412 Sqstm1 agaGACGUCCGGG-ACACGA-AACg ||||| ||| |||| ||| acaCUGCACUCCCACCUGCUCUUGc 2 21 266 290 [mm9:11:50014002-50014026:-] 0.4847 123 0 -21.35 -0.1072 MIMAT0000578 mmu-miR-337-3p 18412 Sqstm1 uccguaGUAUAUCCUCGACUu |:|: ||||||| gguaccCGUGGCUGAGCUGAg 2 16 198 218 [mm9:11:50014074-50014094:-] 0.4744 143 7 -19.75 -0.1035 MIMAT0002105 mmu-miR-464 18412 Sqstm1 auagagugucuuauUUGAACCAu :||||||| auguagcuuccucuGACUUGGUu 2 10 575 597 [mm9:11:50013695-50013717:-] 0.5099 141 7 -11.21 -0.4319 MIMAT0003190 mmu-miR-291b-3p 18412 Sqstm1 uguUUGUUUUACC---UACGUGAAa ||:||||||| |||||||| uguAAUAAAAUGGCAUAUGCACUUu 2 20 609 633 [mm9:11:50013659-50013683:-] 0.5099 174 7 -21.25 -1.0173 MIMAT0004823 mmu-miR-666-3p 18412 Sqstm1 ucguccgcuagugcGACGUCGg ||||||| gccucugcagggaaCUGCAGCa 2 9 243 264 [mm9:11:50014028-50014049:-] 0.4795 140 7 -21.19 -0.2958 MIMAT0003474 mmu-miR-694 18412 Sqstm1 gaaGUCCGUU-GUAAAAGUc | | :|: :||||||| caaCUGCUAGUUAUUUUCAa 2 17 363 382 [mm9:11:50013910-50013929:-] 0.4906 143 7 -7.73 -0.9771 MIMAT0004826 mmu-miR-146b* 18412 Sqstm1 uggUCUUGA-CUCAGGGAUCCCg :|: || || :||||||| cagGGGCCUACAGCUCCUAGGGa 2 20 439 461 [mm9:11:50013831-50013853:-] 0.5099 150 7 -21.40 -0.4360 MIMAT0003495 mmu-miR-705 18412 Sqstm1 acGGGUGGGGUG-GAGGGUGg | ||| |::| ||||||| agCACACACUGCACUCCCACc 2 19 261 281 [mm9:11:50014011-50014031:-] 0.4847 157 7 -28.42 -0.1620 MIMAT0003498 mmu-miR-708* 18412 Sqstm1 gaucuucgagugucaGAUCAAc |||||| ugauuaguacaacugCUAGUUa 2 8 354 375 [mm9:11:50013917-50013938:-] 0.5139 120 6 -10.98 -0.1597 MIMAT0003502 mmu-miR-712 18412 Sqstm1 ccauggcgGGCCCACUUCCUc ||| ||||||| augugaagCCGAAUGAAGGAu 2 14 473 493 [mm9:11:50013799-50013819:-] 0.5099 149 7 -17.64 -0.6002 MIMAT0004837 mmu-miR-615-5p 18412 Sqstm1 cuaggcUCGUGGCCCCUGGGGg ||||| ||||||| gcuuaaAGCAC--AGGACCCCc 2 17 555 574 [mm9:11:50013718-50013737:-] 0.5099 149 7 -26.97 -0.5622 MIMAT0004934 mmu-miR-872 18412 Sqstm1 ggACUUGAUUGUUCAUUGGAa | :::| ::||||||||| acUUGGUUUGUAAGUAACCUg 2 20 590 610 [mm9:11:50013682-50013702:-] 0.5099 159 7 -19.83 -0.7293 MIMAT0004938 mmu-miR-875-3p 18412 Sqstm1 guaucggagucauAAAAGUCc ||||||| aaugugugaugccUUUUCAGg 2 9 114 134 [mm9:11:50014158-50014178:-] 0.5217 140 7 -13.09 -0.3493 MIMAT0005292 mmu-miR-582-3p 18412 Sqstm1 aacccaaGUCA--ACAAGUUGUcc :||| | ||||||| caacugcUAGUUAUUUUCAACAaa 3 16 363 386 [mm9:11:50013906-50013929:-] 0.4906 130 0 -8.76 -0.1681 MIMAT0007868 mmu-miR-1903 18412 Sqstm1 acAGAGUCCUUCUUCUU-CUUCc || :: |||| ||| |||| auUCAUGUGAAGCCGAAUGAAGg 2 21 469 491 [mm9:11:50013801-50013823:-] 0.5099 124 0 -18.25 -0.3131 MIMAT0009391 mmu-miR-1928 18412 Sqstm1 cucgaccGUUACAUCGa | ||||||| aggacccCCAUGUAGCu 2 11 566 582 [mm9:11:50013710-50013726:-] 0.5099 142 7 -11.60 -0.1516 MIMAT0009402 mmu-miR-1938 18412 Sqstm1 cuggcuUGAUGUUCAGGGUGGc |||:| | ||||||| gcacacACUGC-ACUCCCACCu 2 17 262 282 [mm9:11:50014010-50014030:-] 0.4847 154 7 -19.67 -0.1077 MIMAT0015640 mmu-miR-3470a 18412 Sqstm1 ggucggaccagaugUUUCACu |||||| uguuuccuuuauuaAAAGUGa 2 8 336 356 [mm9:11:50013936-50013956:-] 0.5372 120 6 -11.56 -0.1593 MIMAT0000141 mmu-miR-130a 18412 Sqstm1 uacgggaaaAUUGUA-ACGUGAc |::||| |||||| guaauaaaaUGGCAUAUGCACUu 2 14 610 632 [mm9:11:50013660-50013682:-] 0.5099 121 6 -11.83 -1.0301 MIMAT0000147 mmu-miR-135a 18412 Sqstm1 aguguauccuUAUUUUUCGGUAu | | |||||||| uauuuucaacAAAUAAAGCCAUu 2 14 374 396 [mm9:11:50013896-50013918:-] 0.4906 149 7 -9.84 -1.1174 MIMAT0000148 mmu-miR-136 18412 Sqstm1 gguaguAGUUUUGUUUACCUCa || |: :||||||| uacagcUCCUAGGGAAUGGAGa 2 17 447 468 [mm9:11:50013824-50013845:-] 0.5099 148 7 -16.18 -0.2054 MIMAT0000150 mmu-miR-138 18412 Sqstm1 gccggacuaaGUGUUGUGGUCGa ||: :||||||| uugccgccagCAUUGCACCAGCa 2 14 287 309 [mm9:11:50013983-50014005:-] 0.5109 149 7 -21.11 -0.3350 MIMAT0000156 mmu-miR-144 18412 Sqstm1 ucaUGUAGUAG-AUAUGACAu |: |:||| |||||||| aggAUCUUAUCUUAUACUGUc 2 18 489 509 [mm9:11:50013783-50013803:-] 0.5099 160 7 -13.50 -0.4712 MIMAT0000210 mmu-miR-181a 18412 Sqstm1 ugaguggCUGUCGCAACUUACAa || ||: |||||||| gcaugagGAGAGUUUUGAAUGUg 2 17 147 169 [mm9:11:50014123-50014145:-] 0.4744 160 7 -14.75 -0.3894 MIMAT0000238 mmu-miR-205 18412 Sqstm1 gucugaggccacCUUACUUCCu ||||||||| ucaugugaagccGAAUGAAGGa 2 11 471 492 [mm9:11:50013800-50013821:-] 0.5099 150 7 -18.23 -0.7150 MIMAT0000373 mmu-miR-295 18412 Sqstm1 ucUGAGUUUUCAUCAU-CGUGAAa | | ||| | || |||||| guAAUAAAAUGGCAUAUGCACUUu 2 22 610 633 [mm9:11:50013659-50013682:-] 0.5099 121 6 -10.15 -0.8728 MIMAT0000379 mmu-miR-301a 18412 Sqstm1 cgaaacUGUUAUGAUA-ACGUGAc | |||: || |||||| uguaauAAAAUGGCAUAUGCACUu 2 18 609 632 [mm9:11:50013660-50013683:-] 0.5099 121 6 -10.14 -1.0189 MIMAT0000385 mmu-miR-106a 18412 Sqstm1 gauggacgugacaAU-CGUGAAAc || ||||||| uaauaaaauggcaUAUGCACUUUa 2 11 611 634 [mm9:11:50013658-50013681:-] 0.5099 141 7 -10.54 -1.1839 MIMAT0000386 mmu-miR-106b 18412 Sqstm1 uagacgUGACAGU---CGUGAAAu | || || ||||||| uaauaaAAUGGCAUAUGCACUUUa 2 16 611 634 [mm9:11:50013658-50013681:-] 0.5099 142 7 -13.04 -1.1839 MIMAT0000529 mmu-miR-20a 18412 Sqstm1 gauggacgugaUAUUCGUGAAAu ||| ||||||| aauaaaauggcAUAUGCACUUUa 2 13 612 634 [mm9:11:50013658-50013680:-] 0.5099 152 7 -13.04 -1.1821 MIMAT0000540 mmu-miR-93 18412 Sqstm1 gauggacgUGCU-UGU-CGUGAAAc |:|: |:| ||||||| guaauaaaAUGGCAUAUGCACUUUa 2 16 610 634 [mm9:11:50013658-50013682:-] 0.5099 145 7 -11.14 -1.1821 MIMAT0000612 mmu-miR-135b 18412 Sqstm1 aguguauccUUACUUUUCGGUAu ||| |||||||| uuuucaacaAAU--AAAGCCAUu 2 15 376 396 [mm9:11:50013896-50013916:-] 0.4906 147 7 -10.82 -1.1174 MIMAT0000649 mmu-miR-17 18412 Sqstm1 gauggacgugacAUUCGUGAAAc || ||||||| aauaaaauggcaUAUGCACUUUa 2 12 612 634 [mm9:11:50013658-50013680:-] 0.5099 147 7 -10.54 -1.1839 MIMAT0000653 mmu-miR-28 18412 Sqstm1 gaGUUAUCUGACACUCGAGGAa ||: :| || ||||||| ggCAGGGGCCU-ACAGCUCCUa 2 21 437 457 [mm9:11:50013835-50013855:-] 0.5099 146 7 -17.89 -0.1170 MIMAT0000654 mmu-miR-32 18412 Sqstm1 acgUUGAAUCAUUACACGU-UAu |::|| | |||||||| || gagAGUUUUG-AAUGUGCAUAUg 2 20 154 175 [mm9:11:50014117-50014138:-] 0.4744 129 0 -12.54 -0.1545 MIMAT0000663 mmu-miR-218 18412 Sqstm1 ugUACCAAU-CUAG-UUCGUGUu ||| | | | |: ||||||| uaAUGUUAAUGCUUAAAGCACAg 2 20 545 567 [mm9:11:50013725-50013747:-] 0.5099 149 7 -11.02 -0.3670 MIMAT0000667 mmu-miR-33 18412 Sqstm1 acGUUACGUUGAUGU-UACGUg :||| ||: :|| ||||| ugUAAUAAAAUGGCAUAUGCAc 2 20 609 630 [mm9:11:50013662-50013683:-] 0.5099 123 0 -14.90 -0.4650 MIMAT0000669 mmu-miR-221 18412 Sqstm1 cuUUGGGUCGU-CUGUUACAUCGa |:| ||| | | ||||||| aaAGCACAGGACCCCCAUGUAGCu 2 22 559 582 [mm9:11:50013710-50013733:-] 0.5099 152 7 -17.02 -0.1487 MIMAT0000670 mmu-miR-222 18412 Sqstm1 uggGUCAUCGGUCUACAUCGa ||| | || ||||||| gcaCAGGACCCCCAUGUAGCu 2 19 562 582 [mm9:11:50013710-50013730:-] 0.5099 158 7 -19.35 -0.1502 MIMAT0000673 mmu-miR-181b 18412 Sqstm1 uggguggCUGUCGUUACUUACAa || ||: ||||||| gcaugagGAGAGUUUUGAAUGUg 2 17 147 169 [mm9:11:50014123-50014145:-] 0.4744 152 7 -14.58 -0.3894 MIMAT0000674 mmu-miR-181c 18412 Sqstm1 ugaguggCUGUC-CAACUUACAa || || |||||||| gcaugagGAGAGUUUUGAAUGUg 2 16 147 169 [mm9:11:50014123-50014145:-] 0.4744 150 7 -12.18 -0.3955 MIMAT0000741 mmu-miR-377 18412 Sqstm1 uguuuUCAACGGAAACACACUa || || ||||||| ucuucAGGUGGGAAUGUGUGAu 2 18 102 123 [mm9:11:50014169-50014190:-] 0.5217 145 7 -12.66 -0.4206 MIMAT0003151 mmu-miR-378 18412 Sqstm1 ggaagACUGAGGU--UCAGGUCa | :| ||| ||||||| cagcaUUGCACCAGCAGUCCAGa 2 17 294 316 [mm9:11:50013976-50013998:-] 0.5109 147 7 -16.38 -0.2954 MIMAT0000766 mmu-miR-335-5p 18412 Sqstm1 uguaaaaagcaauaACGAGAACu |||||||| acugcacucccaccUGCUCUUGc 2 10 268 290 [mm9:11:50014002-50014024:-] 0.4847 145 7 -11.64 -0.1280 MIMAT0001533 mmu-miR-448 18412 Sqstm1 uacccuguaggaUGUAUACGUu :|||||||| uguaauaaaaugGCAUAUGCAc 2 11 609 630 [mm9:11:50013662-50013683:-] 0.5099 146 7 -11.04 -0.1917 MIMAT0003187 mmu-miR-20b 18412 Sqstm1 gauggaCGUGAUACUCGUGAAAc ||| ||| ||||||| aaaaugGCA-UAU--GCACUUUa 2 18 615 634 [mm9:11:50013658-50013677:-] 0.5099 148 7 -10.54 -1.1682 MIMAT0004186 mmu-miR-301b 18412 Sqstm1 cgaaacUGUUAUGGUA-ACGUGAc | |||: ||| |||||| uguaauAAAAUGGCAUAUGCACUu 2 18 609 632 [mm9:11:50013660-50013683:-] 0.5099 129 6 -13.02 -1.0189 MIMAT0004828 mmu-miR-708 18412 Sqstm1 gggUCGAUCUAACAU-UCGAGGAa :|| :|: || ||||||| gcaGGCAGGGGCCUACAGCUCCUa 2 21 434 457 [mm9:11:50013835-50013858:-] 0.5099 147 7 -19.65 -0.1182 MIMAT0004324 mmu-miR-181d 18412 Sqstm1 uggguggCUGUUGUUACUUACAa || |:: ||||||| gcaugagGAGAGUUUUGAAUGUg 2 17 147 169 [mm9:11:50014123-50014145:-] 0.4744 148 7 -11.94 -0.3924 MIMAT0004943 mmu-miR-653 18412 Sqstm1 gucaucUCUAACAAAGUUGUg || | |||||||| acugcuAGUUAUUUUCAACAa 2 16 365 385 [mm9:11:50013907-50013927:-] 0.4906 151 7 -9.76 -1.2395

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G045671 Sqstm1 Mus musculus 18412 23462932

DNA & RNA Element - RepTar Gene Name miRNA Begin End Profile Sqstm1 mmu-miR-464 beg:582 end:597 pic:3' ATAGAGTGTCTTATTTGAACCAT 5'& ||| .||||||| &5' ---CTCT-------GACTTGGT- 3' Sqstm1 mmu-miR-144 beg:492 end:509 pic:3' TCATGTAGTAG-ATATGACAT 5'& |.||| |||||||| &5' ------TTATCTTATACTGT- 3' Sqstm1 mmu-miR-205 beg:474 end:493 pic:3' GTCTGAGGCCACCTTACTTCCT 5'& || || |||||||||| &5' --GAAGCC----GAATGAAGGA 3' Sqstm1 mmu-miR-1928 beg:564 end:583 pic:3' CTCGACCGT----TACATCGA 5'& || |||||||| &5' -----GGACCCCCATGTAGCT 3' Sqstm1 mmu-miR-221 beg:564 end:583 pic:3' CTTTGGGTCGTCTGTTACATCGA 5'& ..|||| | |||||||| &5' -GGACCC------CCATGTAGCT 3' Sqstm1 mmu-miR-298 beg:234 end:251 pic:3' CCCTTCTTGTCGGGA-GGAGACGG 5'& .|||. ||||||| &5' ---------GGCCTGGCCTCTGC- 3' Sqstm1 mmu-miR-705 beg:264 end:282 pic:3' ACGGGTGGGGTGGAGGGTGG 5'& |||. || |||||||| &5' ----CACTGCA-CTCCCACC 3' Sqstm1 mmu-miR-337-3p beg:201 end:219 pic:3' TCCGTAGTATATCCTCGACTT 5'& |.|. |||||||. &5' ------CGTGGCTGAGCTGAG 3' Sqstm1 mmu-miR-106a beg:618 end:634 pic:3' GATGGACGTGACAATCGTGAAAC 5'& |||. ||||||| &5' ------GCATAT---GCACTTT- 3' Sqstm1 mmu-miR-17 beg:618 end:634 pic:3' GATGGACGTGACATTCGTGAAAC 5'& |||. ||||||| &5' ------GCATAT---GCACTTT- 3' Sqstm1 mmu-miR-20b beg:618 end:634 pic:3' GATGGACGTGATACTCGTGAAAC 5'& |||. ||||||| &5' ------GCATAT---GCACTTT- 3' Sqstm1 mmu-miR-93 beg:618 end:634 pic:3' GATGGACGTGCTTGTCGTGAAAC 5'& |||. ||||||| &5' ------GCATAT---GCACTTT- 3' Sqstm1 mmu-miR-106b beg:618 end:635 pic:3' TAGACGTGACAGTCGTGAAAT 5'& |||. |||||||| &5' ----GCATAT---GCACTTTA 3' Sqstm1 mmu-miR-20a beg:618 end:635 pic:3' GATGGACGTGATATTCGTGAAAT 5'& |||. |||||||| &5' ------GCATAT---GCACTTTA 3' Sqstm1 mmu-miR-335-5p beg:279 end:290 pic:3' TGTAAAAAGCAATAACGAGAACT 5'& |||||||| &5' --------------TGCTCTTG- 3' Sqstm1 mcmv-miR-m01-1 beg:331 end:346 pic:3' GGCAAGCTGCAATAAGAGGAGA 5'& ||| |.||||.| &5' --------CGTG--TTTCCTTT 3' Sqstm1 mcmv-miR-m108-2-5p.2 beg:406 end:428 pic:3' CACTGGCGAGCGCTGCTCACT 5'& |||.| | . .|||||| &5' --GACTGTCCATAGTGAGTGA 3' Sqstm1 mcmv-miR-m59-1 beg:351 end:373 pic:3' GACTGCCAGCTCCGTGACGATT 5'& |||. | |||||||. &5' -TGATTA--GTACAACTGCTAG 3' Sqstm1 mmu-let-7gstar beg:431 end:452 pic:3' CGTTCCGTCACCGGACATGTCA 5'& || |||||| ||||| |||| &5' GC-AGGCAGGGGCCT--ACAG- 3' Sqstm1 mmu-let-7i beg:256 end:277 pic:3' TTGTCGTGTTTGATGATGGAGT 5'& .||||||| |||.| ||| &5' -GCAGCACACACTGCA--CTC- 3' Sqstm1 mmu-miR-106bstar beg:50 end:76 pic:3' CGTCGTTCAT-GGGTGTCACGCC 5'& ||||||.| .|.|.|| || &5' GCAGCAGGGCTTCTATAGATAGG 3' Sqstm1 mmu-miR-1 beg:80 end:95 pic:3' TATGTATGAAGAAATGTAAGGT 5'& |||| .|||||. &5' ---------TCTTGGCATTCT- 3' Sqstm1 mmu-miR-1190 beg:430 end:453 pic:3' CTGTCTCCCCTTGGA-GTCGACT 5'& |.|||. ||..||| ||||| &5' GGCAGGCAGGGGCCTACAGCT-- 3' Sqstm1 mmu-miR-1195 beg:430 end:455 pic:3' ACTCGTCCGA--CCGGAGCTTGAGT 5'& .|||||| ||||| |.||| &5' --GGCAGGCAGGGGCCTACAGCTC- 3' Sqstm1 mmu-miR-122 beg:258 end:278 pic:3' GTTTGTGGTAACAGTGTGAGGT 5'& |.||| .|||||| &5' --AGCACACACT--GCACTCC- 3' Sqstm1 mmu-miR-136 beg:446 end:468 pic:3' GGTAGTAGTTTTGTTTACCTCA 5'& || || |. .||||||| &5' -CAGC-TCCTAGGGAATGGAG- 3' Sqstm1 mmu-miR-138 beg:286 end:309 pic:3' GCCGGACTAAGTGTTGTGGTCGA 5'& ||| ||. .||||||| &5' --GCCGCCAGCATTGCACCAGC- 3' Sqstm1 mmu-miR-141 beg:520 end:539 pic:3' GGTAGAAATGGTCT---GTCACAAT 5'& .||| .|||||| &5' --------GCCACTCTTTAGTGTT- 3' Sqstm1 mmu-miR-146bstar beg:441 end:461 pic:3' TGGTCTTGACTCAGGGATCCCG 5'& .|| || || ||||||| &5' GCCT--AC--AGCTCCTAGGG- 3' Sqstm1 mmu-miR-154star beg:104 end:124 pic:3' TTATCCAGTTGGCACATACTAA 5'& |||| .. |||.|||| &5' ---AGGTGGGAA-TGTGTGAT- 3' Sqstm1 mmu-miR-181a beg:151 end:169 pic:3' TGAGTGGCTGTCGCAACTTACAA 5'& || ||. |||||||| &5' -------GAGAGTTTTGAATGT- 3' Sqstm1 mmu-miR-181b beg:151 end:169 pic:3' TGGGTGGCTGTCGTTACTTACAA 5'& || ||. ||||||| &5' -------GAGAGTTTTGAATGT- 3' Sqstm1 mmu-miR-181c beg:151 end:169 pic:3' TGAGTGGCTGTCC-AACTTACAA 5'& || || |||||||| &5' -------GAGAGTTTTGAATGT- 3' Sqstm1 mmu-miR-181d beg:151 end:169 pic:3' TGGGTGGCTGTTGTTACTTACAA 5'& || |.. ||||||| &5' -------GAGAGTTTTGAATGT- 3' Sqstm1 mmu-miR-185 beg:501 end:520 pic:3' AGTCCTTGACGGAAAGAGAGGT 5'& ||||.| ||.||.| &5' ------ACTGTCCCCCTTTCTA 3' Sqstm1 mmu-miR-188-3p beg:93 end:115 pic:3' ACGTTTGGGACGTACACCCTC 5'& ||.|.| || || |||||| &5' TGTAGAATCTTCAGGTGGGA- 3' Sqstm1 mmu-miR-18a beg:618 end:635 pic:3' GATAGACGTGATCTACGTGGAAT 5'& |||. ||||||.||| &5' ------GCAT---ATGCACTTTA 3' Sqstm1 mmu-miR-18b beg:614 end:635 pic:3' GATTGTCGTGATCTACGTGGAAT 5'& ||..|||. ||||||.||| &5' --AATGGCAT---ATGCACTTTA 3' Sqstm1 mmu-miR-1902 beg:615 end:634 pic:3' TTCAGTACGGATGACGTGGAGA 5'& ||| | |||||.|. &5' -----ATGGCATATGCACTTT- 3' Sqstm1 mmu-miR-1904 beg:41 end:63 pic:3' GGAGGGAGGTCTCCTCGTCTTG 5'& || | .|||| |||||..| &5' --TCACG-TAGAGCAGCAGGGC 3' Sqstm1 mmu-miR-1934 beg:426 end:447 pic:3' TCTCCTGCTTCGTCCCCTGGTCT 5'& ||. |.| |.||||||| || &5' AGGTGGC-AGGCAGGGG-CC--- 3' Sqstm1 mmu-miR-1938 beg:261 end:282 pic:3' CTGGCTTGATGTTCAGGGTGGC 5'& || |||.|| ||||||| &5' -ACAC-ACTGCAC-TCCCACC- 3' Sqstm1 mmu-miR-193star beg:178 end:198 pic:3' AGTAGAACGGGCG--TTTCTGGGT 5'& |||.| | ||||||| &5' -------GCCTGAGAACAGACCCA 3' Sqstm1 mmu-miR-1946a beg:224 end:245 pic:3' TTTTCACACACGGT--GGTGACGGGCCGA 5'& |||. || |||.||| &5' ---------TGCTTTCCCTAGGCCTGGC- 3' Sqstm1 mmu-miR-1948 beg:318 end:329 pic:3' GACATGCTCACGAGACGGATTT 5'& ||||||.| &5' -------------CTGCCTGA- 3' Sqstm1 mmu-miR-1953 beg:213 end:235 pic:3' GTCTTCGGACTCT-TGAAAGGGT 5'& .|||.| .||||||| &5' ---GAGCTTCCTCTGCTTTCCC- 3' Sqstm1 mmu-miR-1954 beg:232 end:253 pic:3' TTGTCCCAGAGT-GAGACGTCA 5'& .||| || . |||||||| &5' --TAGGC-CTGGCCTCTGCAG- 3' Sqstm1 mmu-miR-1960 beg:280 end:302 pic:3' TCGGGAGAAGATTGTCGTGACC 5'& ||.||. | |||||.|| &5' -GCTCTTGCCGC-CAGCATTG- 3' Sqstm1 mmu-miR-1983 beg:100 end:114 pic:3' TCTTTTGTACGAGGTCCACTC 5'& ||.||||||.| &5' ----------CTTCAGGTGGG 3' Sqstm1 mmu-miR-200a beg:520 end:539 pic:3' TGTAGCAATGGTCT---GTCACAAT 5'& .||| .|||||| &5' --------GCCACTCTTTAGTGTT- 3' Sqstm1 mmu-miR-2138 beg:227 end:249 pic:3' TAAGGCGGTTCGGGCAAGGGAA 5'& |||| |.|.|||.| |.|| &5' -TTCC-CTAGGCCTGGCCTCT- 3' Sqstm1 mmu-miR-218 beg:546 end:567 pic:3' TGTACCAATCTAG---TTCGTGTT 5'& |||| |||||||. &5' -----GTTAATGCTTAAAGCACAG 3' Sqstm1 mmu-miR-24 beg:200 end:221 pic:3' GACAAGGA--CGACTTGACTCGGT 5'& || |||||.||||||. &5' -----CCGTGGCTGAGCTGAGCT- 3' Sqstm1 mmu-miR-26bstar beg:172 end:193 pic:3' CTCGGTTCATTACCTCTTGTCC 5'& || | |||||||| &5' --GCTGACGCCT-GAGAACAG- 3' Sqstm1 mmu-miR-28 beg:436 end:457 pic:3' GAGTTATCTGACACTCGAGGAA 5'& ||. .|.| ||||||| &5' --CAG-GGGCCTACAGCTCCT- 3' Sqstm1 mmu-miR-291b-3p beg:612 end:634 pic:3' TGTTTGTTTTACC---TACGTGAAA 5'& |.||||||| ||||||||| &5' ----ATAAAATGGCATATGCACTTT 3' Sqstm1 mmu-miR-298 beg:208 end:230 pic:3' CCCTTCTTGTCG-GGAGGAGACGG 5'& ||.| | |.||||||||. &5' -----GAGCTGAGCTTCCTCTGCT 3' Sqstm1 mmu-miR-339-5p beg:236 end:256 pic:3' GCACTCGAGGACCTCC--TGTCCCT 5'& ||||| .|||||| &5' --------CCTGGCCTCTGCAGGGA 3' Sqstm1 mmu-miR-346 beg:419 end:440 pic:3' TCTCCG--TCCGTGAGCCCGTCTGT 5'& ||| |||. |||||.|| &5' -GAGTGAAAGGT-----GGCAGGCA 3' Sqstm1 mmu-miR-3471 beg:477 end:498 pic:3' TTACGGAATGTCAACCTAGAGT 5'& ||| | ||||||.| &5' ---GCCGAAT-GAAGGATCTTA 3' Sqstm1 mmu-miR-375 beg:468 end:493 pic:3' AGTGCGC-TCGGCTTGCTTGTTT 5'& |||.|.| |||||||.||| .| &5' TCATGTGAAGCCGAATGAAGGA- 3' Sqstm1 mmu-miR-375 beg:172 end:194 pic:3' AGTGCG-CT-CGGCTTGCTTGTTT 5'& |.|| || ||| .| |||||.| &5' --ATGCTGACGCCTGA-GAACAGA 3' Sqstm1 mmu-miR-378 beg:296 end:316 pic:3' GGAAGACTGAGGT--TCAGGTCA 5'& .|| | ||| ||||||| &5' ----TTG-CACCAGCAGTCCAG- 3' Sqstm1 mmu-miR-382star beg:409 end:428 pic:3' TTTTTCACAACAGG---CACTTACT 5'& ||||| ||||.||| &5' ---------TGTCCATAGTGAGTGA 3' Sqstm1 mmu-miR-423-3p beg:194 end:216 pic:3' TGACTCCCCGGAGT-CTGGCTCGA 5'& ||| || |. |.|.||||| &5' ----AGGTACC-CGTGGCTGAGCT 3' Sqstm1 mmu-miR-455 beg:531 end:557 pic:3' CACATATACGGGC-ACCTG-ACG 5'& |||| |.||.|. || ||| &5' GTGTTTGTGTCTAATGTTAATGC 3' Sqstm1 mmu-miR-493 beg:86 end:108 pic:3' GGACCGTGTGT-CATCCTGGAAGT 5'& ||||. |||| |.||||| &5' ---GGCATTCTTGTAGAATCTTCA 3' Sqstm1 mmu-miR-540-3p beg:570 end:594 pic:3' GGTCCTA-GCTGGAGACTGGA 5'& ||| | | ||||||||.| &5' CCATGTAGCTTCCTCTGACTT 3' Sqstm1 mmu-miR-541 beg:300 end:323 pic:3' TCACAC-TGGTTGTA--GTCTTAGGGAA 5'& | ||||.|| ||||||.||| &5' -----GCACCAGCAGTCCAGAATTCCT- 3' Sqstm1 mmu-miR-615-5p beg:554 end:575 pic:3' CTAGGCTCGTGGCCCCTGGGGG 5'& |. ||||| |||||||| &5' --TTAAAGCACA--GGACCCCC 3' Sqstm1 mmu-miR-669e beg:550 end:571 pic:3' TACTTGTACGTG---TGTGTTCTGT 5'& |||| .||||.||| &5' ------ATGCTTAAAGCACAGGAC- 3' Sqstm1 mmu-miR-671-5p beg:49 end:67 pic:3' GAGGTCGGGGAGGTCCCGAAGGA 5'& ||| |||||||||. &5' ----AGCAG---CAGGGCTTCT- 3' Sqstm1 mmu-miR-683 beg:43 end:60 pic:3' CTCCTGTGTCGAATGTCGTCC 5'& ||..|| .||||||| &5' ----ACGTAGA--GCAGCAGG 3' Sqstm1 mmu-miR-696 beg:287 end:309 pic:3' GGGT-GTCGTT-CGTGTGCG 5'& ||. ||||| |||| || &5' -CCGCCAGCATTGCACCAGC 3' Sqstm1 mmu-miR-705 beg:8 end:27 pic:3' ACGGG-TGGGGTGGAGGGTGG 5'& ||| .||||||| ||| &5' -GCCAAGCCCCACC-CCC--- 3' Sqstm1 mmu-miR-708 beg:435 end:457 pic:3' GGGTCGATCTAACAT-TCGAGGAA 5'& .|| .|. ||||||| &5' ---GGCAGGGGCCTACAGCTCCT- 3' Sqstm1 mmu-miR-712 beg:472 end:493 pic:3' CCATGGCGGGCCCACTTCCTC 5'& ||. | ||| ||||||| &5' -GTGAAG-CCGAATGAAGGA- 3' Sqstm1 mmu-miR-764-3p beg:235 end:249 pic:3' TGTCAACGGTGATACCGGAGGA 5'& ||| |||||||. &5' ------GCC----TGGCCTCT- 3' Sqstm1 mmu-miR-872 beg:588 end:610 pic:3' GGACTTGATTGTTCATTGGAA 5'& |.||. .||||||||| &5' CTTGGTTTG-TAAGTAACCT- 3' Sqstm1 mmu-miR-877 beg:206 end:229 pic:3' GGGACGCGGTA-G-AGGAGATG 5'& ||| ||. | ||||||.| &5' --CTGAGCTGAGCTTCCTCTGC 3' Sqstm1 mmu-miR-877 beg:569 end:590 pic:3' GGG-ACG-CGGTAGAGGAGATG 5'& ||| ||. ||. ||||||. &5' CCCATGTAGCT---TCCTCTG- 3' Sqstm1 mmu-miR-92astar beg:4 end:24 pic:3' CATTACGGTGGTTAGGGGTGGA 5'& ||. .|||| ||||||| &5' ----TGTGGCCAAGCCCCACC- 3' Sqstm1 mmu-miR-31 beg:277 end:292 pic:3' GTCGATACGGTCGTAGAACGGA 5'& || || ||||||| &5' --------CCTGC-TCTTGCC- 3'

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score Sqstm1 RAID00118032 mmu-miR-292a-3p miRNA MIMAT0000370 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID00126507 mmu-miR-20b-5p miRNA MIMAT0003187 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID00236693 mmu-miR-106b-5p miRNA MIMAT0000386 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID00293656 mmu-miR-181b-5p miRNA MIMAT0000673 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID00656309 mmu-miR-216c-3p miRNA MIMAT0029889 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID00768820 mmu-miR-218-5p miRNA MIMAT0000663 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID00859487 mmu-miR-3058-5p miRNA MIMAT0014813 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID00997528 mmu-miR-33-5p miRNA MIMAT0000667 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID01328343 mmu-miR-17-5p miRNA MIMAT0000649 Sqstm1 mRNA 18412 Reporter Assay//Western Blot//RT-PCR//FACS (fluorescence-activated cell sorting)//CLIP-seq//Prediction 0.9934 Sqstm1 RAID01389038 mmu-miR-222-3p miRNA MIMAT0000670 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID01486226 mmu-miR-708-5p miRNA MIMAT0004828 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID01521253 mmu-miR-301b-3p miRNA MIMAT0004186 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID01566502 mmu-miR-378c miRNA MIMAT0025138 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID01568862 mmu-miR-136-5p miRNA MIMAT0000148 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID01593952 mmu-miR-301a-3p miRNA MIMAT0000379 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID01682147 mmu-miR-377-3p miRNA MIMAT0000741 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID01754096 mmu-miR-93-5p miRNA MIMAT0000540 Sqstm1 mRNA 18412 Reporter Assay//Western Blot//RT-PCR//FACS (fluorescence-activated cell sorting)//CLIP-seq//Prediction 0.9937 Sqstm1 RAID01895558 mmu-miR-181d-5p miRNA MIMAT0004324 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID01982298 mmu-miR-181a-5p miRNA MIMAT0000210 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID02013493 mmu-miR-20a-5p miRNA MIMAT0000529 Sqstm1 mRNA 18412 Reporter Assay//Western Blot//RT-PCR//FACS (fluorescence-activated cell sorting)//CLIP-seq//Prediction 0.9934 Sqstm1 RAID02021365 mmu-miR-290a-3p miRNA MIMAT0004572 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID02210519 mmu-miR-181c-5p miRNA MIMAT0000674 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID02321650 mmu-miR-221-3p miRNA MIMAT0000669 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID02353328 mmu-miR-135a-5p miRNA MIMAT0000147 Sqstm1 mRNA 18412 Prediction 0.2202 Sqstm1 RAID02353682 mmu-miR-106a-5p miRNA MIMAT0000385 Sqstm1 mRNA 18412 Reporter Assay//Western Blot//RT-PCR//FACS (fluorescence-activated cell sorting)//CLIP-seq//Prediction 0.9934 Sqstm1 RAID02459307 mmu-miR-32-5p miRNA MIMAT0000654 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID02538667 mmu-miR-448-3p miRNA MIMAT0001533 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID02545432 mmu-miR-138-5p miRNA MIMAT0000150 Sqstm1 mRNA 18412 Prediction 0.2202 Sqstm1 RAID02558686 mmu-miR-378a-3p miRNA MIMAT0003151 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID02706901 mmu-miR-653-5p miRNA MIMAT0004943 Sqstm1 mRNA 18412 Prediction 0.2202 Sqstm1 RAID02717157 mmu-miR-135b-5p miRNA MIMAT0000612 Sqstm1 mRNA 18412 Prediction 0.2202 Sqstm1 RAID02984190 mmu-miR-146b-3p miRNA MIMAT0004826 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID03036182 mmu-miR-28a-5p miRNA MIMAT0000653 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID03311765 mmu-miR-295-3p miRNA MIMAT0000373 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID03419505 mmu-miR-6978-3p miRNA MIMAT0027859 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID03560157 mmu-miR-205-5p miRNA MIMAT0000238 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID03580994 mmu-miR-335-5p miRNA MIMAT0000766 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID03594753 mmu-miR-3060-5p miRNA MIMAT0014826 Sqstm1 mRNA 18412 Prediction 0.1828 Sqstm1 RAID03687475 mmu-miR-130a-3p miRNA MIMAT0000141 Sqstm1 mRNA 18412 CLIP-seq//Prediction 0.6308 Sqstm1 RAID03927519 mmu-miR-144-3p miRNA MIMAT0000156 Sqstm1 mRNA 18412 Prediction 0.1828