PTM - CPLM Gene Name UniProt ID Type Position Code Bin1; Amphl; Sh3p9 O08539 Ubiquitination 146 K Bin1; Amphl; Sh3p9 O08539 Ubiquitination 35 K Bin1; Amphl; Sh3p9 O08539 Ubiquitination 53 K Bin1; Amphl; Sh3p9 O08539 Ubiquitination 73 K Bin1; Amphl; Sh3p9 O08539 Ubiquitination 258 K Bin1; Amphl; Sh3p9 O08539 Ubiquitination 272 K Bin1; Amphl; Sh3p9 O08539 Ubiquitination 282 K Bin1; Amphl; Sh3p9 O08539 Ubiquitination 211 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Bin1; Amphl; Sh3p9 O08539 159 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 276 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 286 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 296 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 298 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 304 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 308 T Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 321 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 324 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 328 T Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 332 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 334 S Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 349 T Mus musculus(Mouse) Bin1; Amphl; Sh3p9 O08539 351 S Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O08539 S276-p Phosphorylation SLEkQHGsNTFTVkA O08539 S286-p Phosphorylation FTVkAQPsDNAPEKG O08539 S296-p Phosphorylation APEKGNKsPsPPPDG O08539 S298-p Phosphorylation EKGNKsPsPPPDGsP O08539 S304-p Phosphorylation PsPPPDGsPAAtPEI O08539 T308-p Phosphorylation PDGsPAAtPEIRVNH O08539 S324-p Phosphorylation PEPASGAsPGAtIPK O08539 T328-p Phosphorylation SGAsPGAtIPKsPsQ O08539 S332-p Phosphorylation PGAtIPKsPsQLRKG O08539 S334-p Phosphorylation AtIPKsPsQLRKGPP O08539 T349-p Phosphorylation VPPPPKHtPsKEMKQ O08539 S351-p Phosphorylation PPPKHtPsKEMKQEQ O08539 K35-ub Ubiquitination KVLQKLGkADETKDE O08539 K53-ub Ubiquitination QCVQNFNkQLTEGTR O08539 K73-ub Ubiquitination RTYLASVkAMHEASK O08539 K146-ub Ubiquitination RIAKRGRkLVDYDSA O08539 K211-ub Ubiquitination QAEEELIkAQKVFEE O08539 K258-ub Ubiquitination NFHKEMSkLNQNLND O08539 K272-ub Ubiquitination DVLVSLEkQHGsNTF O08539 K282-ub Ubiquitination GsNTFTVkAQPsDNA

PTM - dbPTM UniProt ID Position Code Type Resources References O08539 296 S Phosphorylation Swiss-Prot 1010711 17114649;17242355;19367708 O08539 298 S Phosphorylation Swiss-Prot 1010711 17114649;17242355;19367708 O08539 304 S Phosphorylation Swiss-Prot 1010711 17114649;17242355 O08539 308 T Phosphorylation Swiss-Prot 1010711 17242355 O08539 324 S Phosphorylation Swiss-Prot 1010711 19367708 O08539 332 S Phosphorylation Swiss-Prot 1010711 19131326 O08539 296 S Phosphorylation PhosphoELM.10011 17114649;17242355 O08539 298 S Phosphorylation PhosphoELM.10011 17114649;17242355;15345747 O08539 304 S Phosphorylation PhosphoELM.10011 17114649;17242355;15345747 O08539 308 T Phosphorylation PhosphoELM.10011 17242355 O08539 286 S Phosphorylation Phosphositeplus.1010730 16452087 O08539 296 S Phosphorylation Phosphositeplus.1010730 16452087;17114649;17242355;18846507;19367708;19655815;19737024;20415495;21183079;21659605 O08539 298 S Phosphorylation Phosphositeplus.1010730 15345747;16452087;17114649;17242355;18779572;18846507;19367708;19655815;19737024;20139300;20415495;20531401;21183079;21659605 O08539 304 S Phosphorylation Phosphositeplus.1010730 15345747;17114649;17242355;19655815;20139300;20415495;20531401;21183079;21659605 O08539 324 S Phosphorylation Phosphositeplus.1010730 19367708;19655815;20415495;20531401;21183079;21659604;21659605 O08539 332 S Phosphorylation Phosphositeplus.1010730 21659605 O08539 351 S Phosphorylation Phosphositeplus.1010730 18846507 O08539 308 T Phosphorylation Phosphositeplus.1010730 17242355;21183079 O08539 296 S Phosphorylation SysPTM 1.1 17242355;18846507 O08539 298 S Phosphorylation SysPTM 1.1 17242355;18846507;18779572 O08539 304 S Phosphorylation SysPTM 1.1 17242355 O08539 324 S Phosphorylation SysPTM 1.1 18846507 O08539 351 S Phosphorylation SysPTM 1.1 18846507 O08539 308 T Phosphorylation SysPTM 1.1 17242355

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O08539 304 S 17114649 HTP Phosphorylation O08539 304 S 17242355 HTP Phosphorylation O08539 304 S 15345747 HTP Phosphorylation O08539 296 S 17114649 HTP Phosphorylation O08539 296 S 17242355 HTP Phosphorylation O08539 298 S 17114649 HTP Phosphorylation O08539 298 S 17242355 HTP Phosphorylation O08539 298 S 15345747 HTP Phosphorylation O08539 308 T 17242355 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O08539 296 Phosphoserine 17242355;21183079 O08539 298 Phosphoserine 17242355;21183079 O08539 304 Phosphoserine 15345747;17242355;21183079 O08539 308 Phosphothreonine 17242355;21183079 O08539 324 Phosphoserine 21183079 O08539 332 Phosphoserine 19131326

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Bin1 IPI00114352 S 286 TVKAQPpSDNAPEK phosphorylation Bin1 IPI00114352 S 296 PEKGNKpSPSPPPD phosphorylation Bin1 IPI00114352 S 298 KGNKSPpSPPPDGS phosphorylation Bin1 IPI00114352 S 304 SPPPDGpSPAATPE phosphorylation Bin1 IPI00114352 S 324 EPASGApSPGATIP phosphorylation Bin1 IPI00114352 S 351 PPKHTPpSKEMKQE phosphorylation Bin1 IPI00114352 T 308 DGSPAApTPEIRVN phosphorylation Bin1 IPI00114352 T 328 GASPGApTIPKSPS phosphorylation

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID Bin1 Mus musculus (Mouse) 146; 35; 53; 258; 272; 282; 73 "146,IAKRGRKLVDYDS; 35,VLQKLGKADETKD; 53,CVQNFNKQLTEGT; 258,FHKEMSKLNQNLN; 272,VLVSLEKQHGSNT; 282,SNTFTVKAQPSDN; 73,TYLASVKAMHEAS" 146:22790023; 35:22790023; 53:22790023; 258:22790023; 272:22790023; 282:22790023; 73:22790023 Bin1 Mus musculus (Mouse) 180; 173 "180,AEEELIKAQKVFE; 173,DEAKIAKAEEELI" 180:22790023; 173:22790023