iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107137

Ensembl Protein ID

ENSSHAP00000015457.1

UniProt Accession

G3WJ52; G3WJ52_SARHA

Genbank Protein ID

ENSSHAP00000015457

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01024103

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013174.1	ENSSHAT00000015584.1	ENSSHAP00000015457.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	79.84	1.00e-178	623.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

SGNMDKSKEN SVSGPSNKTT ILLGEGPKRV PVTQHISSQN RLPASSGQAQ RVLRPSNTLL 60
VSSQTQKNVS SHKAVQTQQS QKLQPAAVIP PTSRPPNNTQ NTEQSQTAVS ASAPGKGETP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGGCAACA TGGACAAATC TAAAGAAAAC AGTGTTTCAG GACCTAGCAA CAAGGTAAAA 60
CTTTATTAGA ACATCAAAAC TTTTGCAGTA GCAGTTATGA AACCTCTAGC CACAAAATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	63.79	1.00e-107	382.00
IUUC-Aml-001426	Ailuropoda melanoleuca	81.77	0.00e+00	643.00
IUUC-Atr-002453	Amborella trichopoda	64.83	2.00e-110	391.00
IUUC-Apl-003626	Anas platyrhynchos	72.84	8.00e-162	563.00
IUUC-Aca-004602	Anolis carolinensis	68.37	2.00e-154	538.00
IUUC-Aly-005878	Arabidopsis lyrata	64.52	3.00e-108	384.00
IUUC-Ath-007117	Arabidopsis thaliana	65.00	1.00e-108	385.00
IUUC-Acl-008199	Aspergillus clavatus	55.09	1.00e-88	320.00
IUUC-Afl-008419	Aspergillus flavus	52.40	3.00e-88	318.00
IUUC-Afu-008751	Aspergillus fumigatus	55.17	1.00e-88	319.00
IUUC-Ani-009181	Aspergillus nidulans	52.58	3.00e-94	338.00
IUUC-Ang-009787	Aspergillus niger	50.61	2.00e-89	322.00
IUUC-Aor-009980	Aspergillus oryzae	52.40	3.00e-88	318.00
IUUC-Ate-010286	Aspergillus terreus	51.68	4.00e-90	324.00
IUUC-Ame-010849	Astyanax mexicanus	60.10	3.00e-132	464.00
IUUC-Bgr-012110	Blumeria graminis	49.87	1.00e-89	323.00
IUUC-Bta-013474	Bos taurus	78.08	0.00e+00	637.00
IUUC-Bci-013756	Botrytis cinerea	50.88	2.00e-96	345.00
IUUC-Bdi-014257	Brachypodium distachyon	63.10	4.00e-107	380.00
IUUC-Bol-016310	Brassica oleracea	64.86	5.00e-106	377.00
IUUC-Bra-017438	Brassica rapa	64.86	4.00e-107	380.00
IUUC-Cel-018157	Caenorhabditis elegans	62.88	7.00e-103	366.00
IUUC-Cja-019282	Callithrix jacchus	77.34	3.00e-178	617.00
IUUC-Cfa-020162	Canis familiaris	81.01	0.00e+00	639.00
IUUC-Cpo-021764	Cavia porcellus	76.47	2.00e-173	601.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	68.05	4.00e-110	390.00
IUUC-Csa-023694	Chlorocebus sabaeus	78.08	1.00e-169	588.00
IUUC-Cho-024350	Choloepus hoffmanni	92.86	4.00e-108	383.00
IUUC-Cin-025542	Ciona intestinalis	74.23	9.00e-120	422.00
IUUC-Csv-025873	Ciona savignyi	73.58	5.00e-121	426.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	53.79	1.00e-81	296.00
IUUC-Cne-026928	Cryptococcus neoformans	61.87	2.00e-97	349.00
IUUC-Cme-027336	Cyanidioschyzon merolae	68.97	2.00e-122	432.00
IUUC-Dre-028198	Danio rerio	58.69	5.00e-136	477.00
IUUC-Dno-029928	Dasypus novemcinctus	81.70	7.00e-176	609.00
IUUC-Dor-030238	Dipodomys ordii	71.67	2.00e-161	561.00
IUUC-Dse-031266	Dothistroma septosporum	52.87	1.00e-94	339.00
IUUC-Dme-032007	Drosophila melanogaster	62.21	7.00e-103	367.00
IUUC-Ete-032911	Echinops telfairi	62.04	3.00e-120	424.00
IUUC-Eca-033749	Equus caballus	80.67	0.00e+00	630.00
IUUC-Eeu-035170	Erinaceus europaeus	77.40	8.00e-178	615.00
IUUC-Fca-035498	Felis catus	81.33	0.00e+00	641.00
IUUC-Fal-037397	Ficedula albicollis	68.28	4.00e-156	544.00
IUUC-Fox-037747	Fusarium oxysporum	51.81	3.00e-93	335.00
IUUC-Fso-038429	Fusarium solani	51.08	1.00e-90	326.00
IUUC-Gmo-039378	Gadus morhua	58.25	1.00e-130	459.00
IUUC-Ggr-039939	Gaeumannomyces graminis	60.29	4.00e-97	347.00
IUUC-Gga-040187	Gallus gallus	70.49	1.00e-158	552.00
IUUC-Gac-042223	Gasterosteus aculeatus	59.41	8.00e-137	479.00
IUUC-Gma-042870	Glycine max	66.67	1.00e-101	362.00
IUUC-Ggo-045617	Gorilla gorilla	78.82	0.00e+00	637.00
IUUC-Hsa-046968	Homo sapiens	79.06	0.00e+00	639.00
IUUC-Hvu-047072	Hordeum vulgare	54.78	5.00e-83	300.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	68.98	8.00e-151	526.00
IUUC-Kpa-049093	Komagataella pastoris	57.09	5.00e-80	291.00
IUUC-Lch-050346	Latimeria chalumnae	67.40	2.00e-154	538.00
IUUC-Lpe-051466	Leersia perrieri	68.54	5.00e-109	387.00
IUUC-Lma-053006	Leptosphaeria maculans	57.99	2.00e-91	328.00
IUUC-Laf-053422	Loxodonta africana	80.05	0.00e+00	644.00
IUUC-Mcc-055245	Macaca mulatta	78.20	1.00e-167	582.00
IUUC-Mor-056952	Magnaporthe oryzae	55.41	8.00e-93	333.00
IUUC-Mpo-057605	Magnaporthe poae	59.35	2.00e-97	348.00
IUUC-Mtr-057726	Medicago truncatula	66.79	4.00e-108	384.00
IUUC-Mla-059174	Melampsora laricipopulina	63.08	2.00e-101	362.00
IUUC-Mga-059562	Meleagris gallopavo	61.98	2.00e-124	439.00
IUUC-Mvi-060305	Microbotryum violaceum	59.34	8.00e-95	340.00
IUUC-Mmr-061588	Microcebus murinus	78.87	0.00e+00	632.00
IUUC-Mdo-061914	Monodelphis domestica	93.54	0.00e+00	748.00
IUUC-Mmu-063288	Mus musculus	76.23	5.00e-174	603.00
IUUC-Mac-064969	Musa acuminata	64.48	2.00e-109	387.00
IUUC-Mpu-066855	Mustela putorius furo	80.93	0.00e+00	637.00
IUUC-Mlu-068046	Myotis lucifugus	79.80	2.00e-180	624.00
IUUC-Nfi-068527	Neosartorya fischeri	55.17	3.00e-88	318.00
IUUC-Ncr-068678	Neurospora crassa	58.89	3.00e-93	335.00
IUUC-Nle-069848	Nomascus leucogenys	78.57	0.00e+00	635.00
IUUC-Opr-070589	Ochotona princeps	74.50	1.00e-165	575.00
IUUC-Ont-071733	Oreochromis niloticus	62.47	1.00e-129	456.00
IUUC-Oan-073399	Ornithorhynchus anatinus	91.89	2.00e-166	577.00
IUUC-Ocu-074063	Oryctolagus cuniculus	76.60	4.00e-179	620.00
IUUC-Oba-075264	Oryza barthii	64.14	5.00e-108	383.00
IUUC-Obr-076048	Oryza brachyantha	65.95	1.00e-107	382.00
IUUC-Ogl-077637	Oryza glaberrima	68.16	8.00e-108	382.00
IUUC-Ogu-078830	Oryza glumaepatula	68.16	4.00e-108	384.00
IUUC-Oin-079150	Oryza indica	64.14	2.00e-108	384.00
IUUC-Olo-080398	Oryza longistaminata	54.61	4.00e-85	307.00
IUUC-Ome-081544	Oryza meridionalis	56.16	4.00e-93	334.00
IUUC-Oni-082250	Oryza nivara	64.14	2.00e-108	384.00
IUUC-Opu-083638	Oryza punctata	63.89	4.00e-108	384.00
IUUC-Oru-084981	Oryza rufipogon	64.14	2.00e-108	384.00
IUUC-Osa-085961	Oryza sativa	64.14	2.00e-108	384.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.58	8.00e-112	396.00
IUUC-Oga-088891	Otolemur garnettii	79.23	0.00e+00	629.00
IUUC-Oar-090021	Ovis aries	77.94	6.00e-179	619.00
IUUC-Ptr-091458	Pan troglodytes	79.31	0.00e+00	640.00
IUUC-Pan-092546	Papio anubis	78.08	2.00e-169	588.00
IUUC-Psi-093280	Pelodiscus sinensis	76.47	3.00e-171	594.00
IUUC-Pma-094298	Petromyzon marinus	79.25	1.00e-125	442.00
IUUC-Pno-094847	Phaeosphaeria nodorum	49.27	4.00e-92	331.00
IUUC-Ppa-095855	Physcomitrella patens	63.44	5.00e-109	386.00
IUUC-Pfo-096428	Poecilia formosa	61.92	2.00e-134	472.00
IUUC-Pab-098696	Pongo abelii	79.36	0.00e+00	629.00
IUUC-Pop-099405	Populus trichocarpa	62.33	4.00e-108	383.00
IUUC-Pca-100740	Procavia capensis	76.11	7.00e-177	612.00
IUUC-Ppe-101854	Prunus persica	67.04	6.00e-109	386.00
IUUC-Pva-103212	Pteropus vampyrus	78.35	1.00e-176	612.00
IUUC-Pgr-103474	Puccinia graminis	63.26	8.00e-101	360.00
IUUC-Ptt-103933	Puccinia triticina	47.14	8.00e-63	233.00
IUUC-Pte-104089	Pyrenophora teres	51.84	3.00e-93	334.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	48.12	1.00e-92	333.00
IUUC-Rno-105057	Rattus norvegicus	76.60	2.00e-175	608.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	52.94	2.00e-102	365.00
IUUC-Spo-108078	Schizosaccharomyces pombe	61.96	3.00e-104	371.00
IUUC-Smo-109288	Selaginella moellendorffii	66.31	8.00e-110	389.00
IUUC-Sit-110246	Setaria italica	62.85	1.00e-107	382.00
IUUC-Sly-111379	Solanum lycopersicum	65.11	2.00e-108	384.00
IUUC-Stu-112777	Solanum tuberosum	66.42	6.00e-108	383.00
IUUC-Sbi-114325	Sorghum bicolor	66.30	7.00e-107	379.00
IUUC-Sre-115203	Sporisorium reilianum	59.40	4.00e-83	301.00
IUUC-Ssc-115361	Sus scrofa	78.41	0.00e+00	632.00
IUUC-Tgu-116967	Taeniopygia guttata	73.46	2.00e-153	535.00
IUUC-Tru-117570	Takifugu rubripes	62.53	7.00e-139	486.00
IUUC-Tsy-119280	Tarsius syrichta	87.91	8.00e-113	400.00
IUUC-Tni-120721	Tetraodon nigroviridis	61.27	5.00e-137	480.00
IUUC-Tca-121494	Theobroma cacao	62.76	2.00e-108	385.00
IUUC-Tre-121869	Trichoderma reesei	52.19	7.00e-95	340.00
IUUC-Tvi-122510	Trichoderma virens	60.59	5.00e-94	337.00
IUUC-Tae-123071	Triticum aestivum	63.79	1.00e-107	382.00
IUUC-Tur-126240	Triticum urartu	63.79	3.00e-107	381.00
IUUC-Tme-126921	Tuber melanosporum	59.93	7.00e-99	353.00
IUUC-Tbe-127872	Tupaia belangeri	74.62	3.00e-162	563.00
IUUC-Ttr-129134	Tursiops truncatus	78.87	7.00e-178	616.00
IUUC-Uma-129412	Ustilago maydis	59.02	1.00e-80	293.00
IUUC-Vda-130003	Verticillium dahliae	47.23	3.00e-93	335.00
IUUC-Vvi-131272	Vitis vinifera	66.67	2.00e-108	385.00
IUUC-Xtr-132019	Xenopus tropicalis	69.01	5.00e-154	536.00
IUUC-Xma-134203	Xiphophorus maculatus	62.12	6.00e-140	490.00
IUUC-Yli-134503	Yarrowia lipolytica	51.67	2.00e-90	325.00
IUUC-Zma-135232	Zea mays	62.50	2.00e-107	382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence