iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	39.00	1.00e-76	285.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Present with 3050 molecules/cell in log phase SD medium.

Protein Sequence
(Fasta)

MDSVMVKKEV LENPDHDLKR KLEENKEEEN SLSTTSKSKR QVIVPVCMPK IHYSPLKTGL 60
CYDVRMRYHA KIFTSYFEYI DPHPEDPRRI YRIYKILAEN GLINDPTLSG VDDLGDLMLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTCTG TAATGGTTAA GAAAGAAGTA CTGGAAAATC CAGACCATGA TTTAAAAAGA 60
AAGCTAGAAG AGAACAAAGA AGAAGAGAAT AGCCTCTCTA CTACTTCTAA AAGTAAAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR019154--Arb2_domain
IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR017321--Hist_deAcase_II_yeast

Pfam

PF09757--Arb2
PF00850--Hist_deacetyl

PRINTS

PR01270--HDASUPER

Gene Ontology

GO:0070823--C:HDA1 complex
GO:0003682--F:chromatin binding
GO:0042802--F:identical protein binding
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0031047--P:gene silencing by RNA
GO:0010978--P:gene silencing involved in chronological cell aging
GO:0016575--P:histone deacetylation
GO:0001308--P:negative regulation of chromatin silencing involved in replicative cell aging
GO:0010621--P:negative regulation of transcription by transcription factor localization
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0031938--P:regulation of chromatin silencing at telomere
GO:0006351--P:transcription, DNA-templated

KEGG

sce:YNL021W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	38.39	3.00e-65	241.00
IUUC-Aml-002087	Ailuropoda melanoleuca	39.74	6.00e-81	293.00
IUUC-Atr-002745	Amborella trichopoda	37.50	1.00e-77	282.00
IUUC-Apl-003250	Anas platyrhynchos	36.56	2.00e-68	252.00
IUUC-Aca-004303	Anolis carolinensis	39.60	5.00e-84	304.00
IUUC-Aly-006432	Arabidopsis lyrata	41.33	1.00e-70	258.00
IUUC-Ath-007355	Arabidopsis thaliana	39.04	2.00e-73	268.00
IUUC-Ago-007972	Ashbya gossypii	73.93	0.00e+00	1063.00
IUUC-Acl-008187	Aspergillus clavatus	41.44	6.00e-148	516.00
IUUC-Afl-008399	Aspergillus flavus	36.61	3.00e-92	330.00
IUUC-Afu-008954	Aspergillus fumigatus	48.94	4.00e-103	366.00
IUUC-Ani-009142	Aspergillus nidulans	40.74	3.00e-133	467.00
IUUC-Ang-009522	Aspergillus niger	31.70	3.00e-57	214.00
IUUC-Aor-010069	Aspergillus oryzae	38.39	1.00e-134	471.00
IUUC-Ate-010291	Aspergillus terreus	40.67	7.00e-139	485.00
IUUC-Ame-010780	Astyanax mexicanus	42.13	5.00e-85	307.00
IUUC-Bta-013052	Bos taurus	41.49	3.00e-75	275.00
IUUC-Bci-013789	Botrytis cinerea	39.57	2.00e-134	471.00
IUUC-Bdi-014007	Brachypodium distachyon	40.11	4.00e-76	276.00
IUUC-Bol-015468	Brassica oleracea	39.84	5.00e-74	270.00
IUUC-Bra-016680	Brassica rapa	39.84	8.00e-74	269.00
IUUC-Cel-018220	Caenorhabditis elegans	40.77	2.00e-70	258.00
IUUC-Cja-019473	Callithrix jacchus	38.89	1.00e-78	286.00
IUUC-Cfa-020263	Canis familiaris	39.49	9.00e-80	290.00
IUUC-Cpo-021691	Cavia porcellus	41.84	5.00e-82	297.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	46.52	4.00e-56	208.00
IUUC-Csa-024223	Chlorocebus sabaeus	36.67	3.00e-78	285.00
IUUC-Cho-025047	Choloepus hoffmanni	39.02	2.30e-01	28.90
IUUC-Csv-026359	Ciona savignyi	39.15	5.00e-54	202.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	39.50	4.00e-118	416.00
IUUC-Cne-026978	Cryptococcus neoformans	36.83	3.00e-113	400.00
IUUC-Dre-028820	Danio rerio	41.90	1.00e-83	303.00
IUUC-Dno-029160	Dasypus novemcinctus	40.21	2.00e-77	282.00
IUUC-Dor-030859	Dipodomys ordii	41.49	3.00e-85	308.00
IUUC-Dse-031186	Dothistroma septosporum	35.79	5.00e-128	449.00
IUUC-Dme-031963	Drosophila melanogaster	35.57	8.00e-75	273.00
IUUC-Ete-032279	Echinops telfairi	34.31	1.00e-59	222.00
IUUC-Eca-033842	Equus caballus	41.71	2.00e-79	288.00
IUUC-Eeu-034487	Erinaceus europaeus	51.01	3.00e-57	214.00
IUUC-Fca-036430	Felis catus	40.00	7.00e-81	293.00
IUUC-Fox-038067	Fusarium oxysporum	41.75	3.00e-122	430.00
IUUC-Fso-038263	Fusarium solani	39.09	2.00e-139	487.00
IUUC-Gmo-038473	Gadus morhua	42.31	4.00e-66	244.00
IUUC-Ggr-040062	Gaeumannomyces graminis	39.25	3.00e-133	466.00
IUUC-Gga-040501	Gallus gallus	36.56	3.00e-68	251.00
IUUC-Gac-042335	Gasterosteus aculeatus	36.34	2.00e-69	255.00
IUUC-Gma-043738	Glycine max	40.29	1.00e-70	259.00
IUUC-Ggo-045022	Gorilla gorilla	38.54	4.00e-78	284.00
IUUC-Hsa-046904	Homo sapiens	39.00	4.00e-78	284.00
IUUC-Hvu-047285	Hordeum vulgare	39.77	8.00e-72	261.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	42.97	6.00e-87	313.00
IUUC-Kpa-049281	Komagataella pastoris	62.17	0.00e+00	889.00
IUUC-Lch-050330	Latimeria chalumnae	43.12	2.00e-76	278.00
IUUC-Lpe-051214	Leersia perrieri	40.23	2.00e-71	261.00
IUUC-Loc-052231	Lepisosteus oculatus	38.04	9.00e-68	249.00
IUUC-Lma-053263	Leptosphaeria maculans	41.13	7.00e-153	532.00
IUUC-Laf-053386	Loxodonta africana	38.35	7.00e-77	280.00
IUUC-Mcc-055530	Macaca mulatta	36.22	2.00e-78	285.00
IUUC-Meu-056442	Macropus eugenii	40.43	6.00e-80	290.00
IUUC-Mor-057095	Magnaporthe oryzae	38.84	3.00e-135	473.00
IUUC-Mpo-057389	Magnaporthe poae	39.70	7.00e-133	465.00
IUUC-Mtr-058463	Medicago truncatula	42.73	2.00e-79	288.00
IUUC-Mla-059143	Melampsora laricipopulina	38.08	4.00e-104	370.00
IUUC-Mmr-060637	Microcebus murinus	43.15	2.00e-74	272.00
IUUC-Mdo-062198	Monodelphis domestica	40.68	1.00e-78	286.00
IUUC-Mmu-063346	Mus musculus	42.02	3.00e-82	298.00
IUUC-Mac-064630	Musa acuminata	41.74	1.00e-74	271.00
IUUC-Mpu-065884	Mustela putorius furo	37.03	5.00e-81	294.00
IUUC-Mlu-068117	Myotis lucifugus	40.48	4.00e-79	288.00
IUUC-Nfi-068404	Neosartorya fischeri	40.74	5.00e-146	509.00
IUUC-Ncr-068672	Neurospora crassa	40.18	1.00e-141	494.00
IUUC-Nle-069868	Nomascus leucogenys	35.98	8.00e-69	253.00
IUUC-Opr-071074	Ochotona princeps	41.60	3.00e-87	314.00
IUUC-Ont-072246	Oreochromis niloticus	41.56	5.00e-85	307.00
IUUC-Oan-073275	Ornithorhynchus anatinus	36.52	1.00e-68	252.00
IUUC-Ocu-074627	Oryctolagus cuniculus	40.93	2.00e-85	309.00
IUUC-Oba-075489	Oryza barthii	40.58	3.00e-73	267.00
IUUC-Obr-076150	Oryza brachyantha	40.47	4.00e-74	270.00
IUUC-Ogl-077437	Oryza glaberrima	40.58	2.00e-73	268.00
IUUC-Ogu-078370	Oryza glumaepatula	40.58	2.00e-73	268.00
IUUC-Oin-079210	Oryza indica	40.58	2.00e-73	268.00
IUUC-Olo-080971	Oryza longistaminata	44.13	1.00e-68	252.00
IUUC-Oni-082031	Oryza nivara	40.58	3.00e-73	267.00
IUUC-Opu-083471	Oryza punctata	39.36	9.00e-73	265.00
IUUC-Oru-084755	Oryza rufipogon	40.58	2.00e-73	268.00
IUUC-Osa-085447	Oryza sativa	40.58	2.00e-73	268.00
IUUC-Ola-087031	Oryzias latipes	35.51	8.00e-70	256.00
IUUC-Oga-089155	Otolemur garnettii	36.25	1.00e-75	276.00
IUUC-Oar-089620	Ovis aries	41.76	9.00e-78	283.00
IUUC-Ptr-091116	Pan troglodytes	37.77	3.00e-71	261.00
IUUC-Pan-092340	Papio anubis	39.00	7.00e-78	284.00
IUUC-Psi-093734	Pelodiscus sinensis	36.65	7.00e-69	253.00
IUUC-Pma-094386	Petromyzon marinus	40.00	5.00e-74	271.00
IUUC-Pno-095131	Phaeosphaeria nodorum	47.12	6.00e-102	362.00
IUUC-Ppa-095550	Physcomitrella patens	38.40	4.00e-74	270.00
IUUC-Pfo-096110	Poecilia formosa	41.33	8.00e-84	303.00
IUUC-Pab-098422	Pongo abelii	35.13	1.00e-70	259.00
IUUC-Pop-099174	Populus trichocarpa	40.58	3.00e-72	264.00
IUUC-Pca-100833	Procavia capensis	40.11	9.00e-74	270.00
IUUC-Ppe-101644	Prunus persica	40.29	8.00e-75	272.00
IUUC-Pva-102410	Pteropus vampyrus	39.63	4.00e-74	271.00
IUUC-Ptt-103841	Puccinia triticina	30.17	2.00e-96	344.00
IUUC-Pte-104383	Pyrenophora teres	40.03	1.00e-149	521.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	41.67	2.00e-137	481.00
IUUC-Rno-105131	Rattus norvegicus	42.02	9.00e-87	313.00
IUUC-Sha-106661	Sarcophilus harrisii	41.43	5.00e-74	270.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	41.24	3.00e-154	536.00
IUUC-Spo-108300	Schizosaccharomyces pombe	41.02	1.00e-149	521.00
IUUC-Smo-109615	Selaginella moellendorffii	41.93	1.00e-79	288.00
IUUC-Sit-110160	Setaria italica	39.88	2.00e-68	251.00
IUUC-Sly-111164	Solanum lycopersicum	35.75	7.00e-76	276.00
IUUC-Stu-112685	Solanum tuberosum	41.24	4.00e-72	263.00
IUUC-Sar-113692	Sorex araneus	33.33	1.00e-50	193.00
IUUC-Sbi-114301	Sorghum bicolor	40.23	1.00e-69	255.00
IUUC-Sre-115013	Sporisorium reilianum	34.14	6.00e-108	382.00
IUUC-Ssc-115724	Sus scrofa	43.45	6.00e-71	260.00
IUUC-Tgu-116605	Taeniopygia guttata	41.98	6.00e-78	283.00
IUUC-Tru-117614	Takifugu rubripes	41.71	3.00e-84	305.00
IUUC-Tsy-118807	Tarsius syrichta	39.14	2.00e-67	249.00
IUUC-Tni-119809	Tetraodon nigroviridis	43.13	6.00e-85	306.00
IUUC-Tca-121312	Theobroma cacao	40.74	5.00e-76	276.00
IUUC-Tre-121930	Trichoderma reesei	39.20	1.00e-137	481.00
IUUC-Tvi-122373	Trichoderma virens	39.23	2.00e-134	471.00
IUUC-Tae-123064	Triticum aestivum	36.46	2.00e-68	250.00
IUUC-Tme-127027	Tuber melanosporum	40.72	9.00e-97	345.00
IUUC-Tbe-127675	Tupaia belangeri	39.77	1.00e-24	106.00
IUUC-Ttr-128411	Tursiops truncatus	42.32	2.00e-74	272.00
IUUC-Uma-129408	Ustilago maydis	32.78	8.00e-96	342.00
IUUC-Vda-129994	Verticillium dahliae	39.41	6.00e-133	466.00
IUUC-Vpa-130525	Vicugna pacos	48.28	1.00e-13	69.70
IUUC-Vvi-131038	Vitis vinifera	40.12	8.00e-75	272.00
IUUC-Xtr-132618	Xenopus tropicalis	43.65	3.00e-89	321.00
IUUC-Xma-133730	Xiphophorus maculatus	41.07	4.00e-84	304.00
IUUC-Yli-134680	Yarrowia lipolytica	49.34	0.00e+00	703.00
IUUC-Zma-135110	Zea mays	39.47	7.00e-68	249.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence