iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
CPLM	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-07	31.5	155	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++   d  l+lpC H f+++C+ kw      s ++ +CP+Cr
   Q: 155  CCICMDGRAD--LILPCAHSFCQKCIDKW------SDRHRNCPICR 192
           ******9999..55***************......**********8 PP

Organism

Rattus norvegicus

Functional Description
(View)

May be involved in spermatogenesis.

Protein Sequence
(Fasta)

MGQQISDQTQ LVINKLPEKV AKHVTLVRES GSLTYEEFLG RVAELNDVTA KIAAGQEKHL 60
LFEVQPGSDS SAFWKVVVRV VCTKINKSSG IVEASRIMNL YQFIQLYKDI TSQAAGVLAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTTTAGCT AAGCAGCGGC CAAGGCGGCG TCGCTGGCGC GGGGAGAGCG ATGCCTTGAA 60
CAGGGTGAGC CTTCCAGCGC CGCCCCTTTG TCGTGTCCCT TCTCAGCCCC TCCAAGGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-0519--Myristate
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016020--C:membrane
GO:0003677--F:DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination
GO:0006355--P:regulation of transcription, DNA-templated

KEGG

rno:308900

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000996	Aegilops tauschii	37.31	8.00e-09	53.50
IUUC-Aml-001667	Ailuropoda melanoleuca	94.78	6.00e-132	462.00
IUUC-Atr-002441	Amborella trichopoda	41.54	4.00e-10	58.20
IUUC-Apl-003740	Anas platyrhynchos	84.58	2.00e-117	414.00
IUUC-Aca-004541	Anolis carolinensis	83.48	3.00e-117	413.00
IUUC-Ame-011210	Astyanax mexicanus	76.52	4.00e-106	376.00
IUUC-Bta-012755	Bos taurus	96.09	7.00e-133	465.00
IUUC-Bdi-014630	Brachypodium distachyon	38.81	1.00e-09	57.00
IUUC-Bra-016994	Brassica rapa	39.68	2.00e-08	52.80
IUUC-Cel-018183	Caenorhabditis elegans	27.50	6.00e-17	80.50
IUUC-Cja-019484	Callithrix jacchus	96.52	4.00e-125	440.00
IUUC-Cfa-020513	Canis familiaris	95.65	2.00e-133	467.00
IUUC-Cpo-021640	Cavia porcellus	96.09	3.00e-132	463.00
IUUC-Csa-023929	Chlorocebus sabaeus	98.26	2.00e-135	474.00
IUUC-Cho-024712	Choloepus hoffmanni	92.42	3.00e-70	257.00
IUUC-Dre-027893	Danio rerio	75.65	4.00e-104	370.00
IUUC-Dno-029490	Dasypus novemcinctus	93.91	3.00e-130	457.00
IUUC-Dor-030614	Dipodomys ordii	58.19	2.00e-43	167.00
IUUC-Ete-032783	Echinops telfairi	77.67	5.00e-94	336.00
IUUC-Eca-034396	Equus caballus	96.09	5.00e-133	466.00
IUUC-Eeu-035127	Erinaceus europaeus	90.87	1.00e-125	442.00
IUUC-Fca-036513	Felis catus	90.43	6.00e-125	439.00
IUUC-Fal-037395	Ficedula albicollis	84.78	2.00e-119	421.00
IUUC-Fso-038096	Fusarium solani	35.38	3.00e-07	48.50
IUUC-Gmo-039655	Gadus morhua	73.48	3.00e-102	363.00
IUUC-Gga-040726	Gallus gallus	83.48	3.00e-107	380.00
IUUC-Gac-042012	Gasterosteus aculeatus	74.78	6.00e-105	372.00
IUUC-Gma-043685	Glycine max	40.30	2.00e-10	58.90
IUUC-Ggo-044554	Gorilla gorilla	98.26	2.00e-135	474.00
IUUC-Hsa-047009	Homo sapiens	98.26	2.00e-135	474.00
IUUC-Itr-047975	Ictidomys tridecemlineatus	96.52	1.00e-132	465.00
IUUC-Lch-050250	Latimeria chalumnae	79.17	2.00e-113	401.00
IUUC-Lpe-050730	Leersia perrieri	38.81	1.00e-09	56.60
IUUC-Loc-052562	Lepisosteus oculatus	82.61	1.00e-110	391.00
IUUC-Laf-053522	Loxodonta africana	93.91	5.00e-130	456.00
IUUC-Mcc-054924	Macaca mulatta	98.26	2.00e-135	474.00
IUUC-Meu-056708	Macropus eugenii	70.56	9.00e-91	326.00
IUUC-Mtr-057890	Medicago truncatula	37.33	3.00e-09	55.50
IUUC-Mga-059628	Meleagris gallopavo	82.17	5.00e-108	383.00
IUUC-Mmr-061571	Microcebus murinus	96.96	2.00e-134	471.00
IUUC-Mdo-062852	Monodelphis domestica	90.04	5.00e-124	436.00
IUUC-Mmu-063260	Mus musculus	99.13	1.00e-136	478.00
IUUC-Mac-064729	Musa acuminata	37.68	9.00e-11	60.50
IUUC-Mpu-066728	Mustela putorius furo	94.78	6.00e-132	462.00
IUUC-Mlu-068171	Myotis lucifugus	95.65	4.00e-132	463.00
IUUC-Nle-069598	Nomascus leucogenys	98.26	2.00e-135	474.00
IUUC-Opr-070440	Ochotona princeps	72.17	4.00e-89	320.00
IUUC-Ont-072220	Oreochromis niloticus	76.52	8.00e-106	375.00
IUUC-Oan-073618	Ornithorhynchus anatinus	91.30	3.00e-124	437.00
IUUC-Ocu-074638	Oryctolagus cuniculus	96.09	3.00e-133	466.00
IUUC-Oba-075867	Oryza barthii	38.81	3.00e-09	55.80
IUUC-Obr-076083	Oryza brachyantha	37.88	5.00e-09	54.70
IUUC-Ogl-077580	Oryza glaberrima	39.39	2.00e-09	56.20
IUUC-Ogu-078162	Oryza glumaepatula	38.81	2.00e-09	55.80
IUUC-Oin-079986	Oryza indica	38.81	1.00e-09	56.60
IUUC-Olo-080306	Oryza longistaminata	39.39	2.00e-09	56.20
IUUC-Ome-081355	Oryza meridionalis	38.24	1.00e-09	56.60
IUUC-Oni-082456	Oryza nivara	39.39	1.00e-09	56.60
IUUC-Opu-084086	Oryza punctata	38.81	2.00e-09	56.20
IUUC-Oru-084301	Oryza rufipogon	39.39	1.00e-09	56.60
IUUC-Osa-085728	Oryza sativa	38.24	4.00e-09	55.10
IUUC-Ola-086610	Oryzias latipes	73.28	7.00e-99	352.00
IUUC-Olu-087723	Ostreococcus lucimarinus	40.48	2.00e-06	47.80
IUUC-Oga-089014	Otolemur garnettii	95.69	2.00e-130	457.00
IUUC-Oar-089731	Ovis aries	96.96	2.00e-134	471.00
IUUC-Ptr-091461	Pan troglodytes	96.96	2.00e-133	467.00
IUUC-Pan-092822	Papio anubis	98.26	2.00e-135	474.00
IUUC-Psi-093268	Pelodiscus sinensis	83.48	1.00e-109	388.00
IUUC-Pma-094294	Petromyzon marinus	48.48	9.00e-62	229.00
IUUC-Ppa-095463	Physcomitrella patens	35.71	5.00e-09	54.70
IUUC-Pfo-097386	Poecilia formosa	76.09	9.00e-105	372.00
IUUC-Pab-098668	Pongo abelii	92.17	8.00e-124	436.00
IUUC-Pop-099490	Populus trichocarpa	40.30	3.00e-10	58.50
IUUC-Pca-100715	Procavia capensis	89.58	6.00e-73	265.00
IUUC-Ppe-101436	Prunus persica	40.00	6.00e-09	54.30
IUUC-Pva-102192	Pteropus vampyrus	96.09	5.00e-126	442.00
IUUC-Sha-107102	Sarcophilus harrisii	90.04	9.00e-120	422.00
IUUC-Smo-109000	Selaginella moellendorffii	36.62	6.00e-10	57.80
IUUC-Sit-110346	Setaria italica	38.81	2.00e-09	56.20
IUUC-Sly-111299	Solanum lycopersicum	39.39	3.00e-09	55.50
IUUC-Stu-112196	Solanum tuberosum	38.81	6.00e-09	54.30
IUUC-Sar-113049	Sorex araneus	94.78	1.00e-130	458.00
IUUC-Sbi-114022	Sorghum bicolor	38.81	8.00e-10	57.00
IUUC-Ssc-115234	Sus scrofa	95.67	4.00e-132	463.00
IUUC-Tgu-116861	Taeniopygia guttata	84.78	2.00e-119	421.00
IUUC-Tru-118629	Takifugu rubripes	74.78	3.00e-105	373.00
IUUC-Tsy-119495	Tarsius syrichta	98.70	6.00e-136	476.00
IUUC-Tni-120480	Tetraodon nigroviridis	73.91	2.00e-103	367.00
IUUC-Tca-121345	Theobroma cacao	40.79	1.00e-10	60.10
IUUC-Tae-123570	Triticum aestivum	30.00	2.00e-09	56.20
IUUC-Tbe-128140	Tupaia belangeri	64.84	2.00e-60	224.00
IUUC-Ttr-128354	Tursiops truncatus	96.93	7.00e-133	466.00
IUUC-Vpa-130742	Vicugna pacos	95.22	2.00e-132	464.00
IUUC-Vvi-130899	Vitis vinifera	37.66	1.00e-09	56.20
IUUC-Xtr-132961	Xenopus tropicalis	77.73	1.00e-109	389.00
IUUC-Xma-133082	Xiphophorus maculatus	77.90	2.00e-81	294.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence