iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062686

Ensembl Protein ID

ENSMODP00000034258.1

UniProt Accession

Q28463; Q28463_MONDO

Genbank Protein ID

AAB51657.1

Protein Name

Recombination-activating protein

Genbank Nucleotide ID

U51897

Gene Name

RAG1; RAG-1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000024470.1	ENSMODT00000035844.1	ENSMODP00000034258.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	82.33	0.00e+00	1805.00	IUUC-Hsa-045964
E3 activity/RING/RING	79.56	0.00e+00	1754.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MEISVAPSQG LRPVPDEIQY PHMKFSEWKF KLFKVRSSVK PSPGEAQGPS KNTMEGQSSL 60
EETPVVICNT NIPAPEKPAL VQPTFTANSK SLEKPADIGK AGEKAIHQAS LRQLCRICGA 120

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Nucleotide Sequence
(Fasta)

ATGGAAATAT CTGTGGCACC GAGTCAAGGA CTTCGCCCAG TACCAGATGA AATCCAGTAC 60
CCACACATGA AATTTTCTGA ATGGAAATTT AAGCTCTTCA AAGTGAGATC CTCTGTGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF00097--zf-C3HC4
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

KEGG

mdo:100011241

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	81.85	0.00e+00	1745.00
IUUC-Apl-003271	Anas platyrhynchos	76.68	0.00e+00	1645.00
IUUC-Aca-004400	Anolis carolinensis	73.05	0.00e+00	1589.00
IUUC-Ame-011295	Astyanax mexicanus	57.50	0.00e+00	1201.00
IUUC-Bta-012421	Bos taurus	81.54	0.00e+00	1747.00
IUUC-Cja-019891	Callithrix jacchus	81.57	0.00e+00	1714.00
IUUC-Cfa-020740	Canis familiaris	76.12	0.00e+00	1663.00
IUUC-Cpo-021800	Cavia porcellus	80.74	0.00e+00	1680.00
IUUC-Csa-024203	Chlorocebus sabaeus	80.51	0.00e+00	1530.00
IUUC-Dre-028416	Danio rerio	57.92	0.00e+00	1188.00
IUUC-Dno-029101	Dasypus novemcinctus	81.98	0.00e+00	1727.00
IUUC-Eca-033385	Equus caballus	82.23	0.00e+00	1749.00
IUUC-Fca-036545	Felis catus	82.29	0.00e+00	1752.00
IUUC-Fal-037208	Ficedula albicollis	74.30	0.00e+00	1618.00
IUUC-Gmo-039622	Gadus morhua	54.45	0.00e+00	1175.00
IUUC-Gga-041182	Gallus gallus	74.81	0.00e+00	1583.00
IUUC-Gac-041682	Gasterosteus aculeatus	56.24	0.00e+00	1189.00
IUUC-Ggo-044510	Gorilla gorilla	82.23	0.00e+00	1743.00
IUUC-Hsa-045964	Homo sapiens	82.33	0.00e+00	1746.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	80.99	0.00e+00	1731.00
IUUC-Lch-050041	Latimeria chalumnae	68.31	0.00e+00	1453.00
IUUC-Loc-052464	Lepisosteus oculatus	61.94	0.00e+00	1331.00
IUUC-Laf-053544	Loxodonta africana	82.62	0.00e+00	1769.00
IUUC-Mcc-054867	Macaca mulatta	81.76	0.00e+00	1738.00
IUUC-Meu-055986	Macropus eugenii	91.56	0.00e+00	1778.00
IUUC-Mga-059262	Meleagris gallopavo	75.10	0.00e+00	1596.00
IUUC-Mmu-064297	Mus musculus	79.47	0.00e+00	1734.00
IUUC-Mpu-066027	Mustela putorius furo	80.99	0.00e+00	1724.00
IUUC-Mlu-067885	Myotis lucifugus	82.04	0.00e+00	1755.00
IUUC-Nle-070073	Nomascus leucogenys	81.76	0.00e+00	1736.00
IUUC-Ont-071400	Oreochromis niloticus	59.65	0.00e+00	1241.00
IUUC-Oan-072920	Ornithorhynchus anatinus	93.91	0.00e+00	784.00
IUUC-Ocu-074616	Oryctolagus cuniculus	81.28	0.00e+00	1727.00
IUUC-Ola-086828	Oryzias latipes	58.51	0.00e+00	1226.00
IUUC-Oga-088675	Otolemur garnettii	91.51	4.00e-151	526.00
IUUC-Oar-090380	Ovis aries	80.42	0.00e+00	1748.00
IUUC-Ptr-090648	Pan troglodytes	82.43	0.00e+00	1749.00
IUUC-Pan-092036	Papio anubis	81.66	0.00e+00	1733.00
IUUC-Psi-093130	Pelodiscus sinensis	79.71	0.00e+00	1726.00
IUUC-Pfo-097273	Poecilia formosa	59.07	0.00e+00	1197.00
IUUC-Pca-100134	Procavia capensis	77.67	0.00e+00	1643.00
IUUC-Rno-105632	Rattus norvegicus	79.66	0.00e+00	1736.00
IUUC-Sha-107238	Sarcophilus harrisii	89.97	0.00e+00	1972.00
IUUC-Sar-113591	Sorex araneus	71.72	0.00e+00	1501.00
IUUC-Ssc-115720	Sus scrofa	80.61	0.00e+00	1714.00
IUUC-Tgu-117030	Taeniopygia guttata	75.54	0.00e+00	1615.00
IUUC-Tru-117669	Takifugu rubripes	55.84	0.00e+00	1133.00
IUUC-Tsy-119578	Tarsius syrichta	77.75	0.00e+00	1664.00
IUUC-Tni-120073	Tetraodon nigroviridis	57.02	0.00e+00	1182.00
IUUC-Tbe-128029	Tupaia belangeri	71.79	0.00e+00	816.00
IUUC-Ttr-128677	Tursiops truncatus	89.16	0.00e+00	771.00
IUUC-Vpa-130346	Vicugna pacos	91.40	0.00e+00	854.00
IUUC-Xtr-132442	Xenopus tropicalis	86.60	1.00e-99	355.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence