iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.20e-17	61.7	226	364

Active Site

Position(s)	Description	Evidence
322	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp...egisakpvdesdltewevlilG.pedtpYe...........ggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvC 82
           Rl+kel ++ ++     + +s+++v+e  ++ew++ +    +d+p +           +    l+i f+e+YPf+PP v+++ +i ++ +    G++C
   Q: 226  RLMKELRDIYRSDAfkkNMYSIELVNE-SIYEWNIRLKSvDPDSPLHsdlqmlkekegKDSILLNILFKETYPFEPPFVRVVHPIISGGYVLIgGAIC 322
           566666666554432324455555555.4666666665443444443111111111112245689*******************9999888777**** PP
   S: 83   lsilkeeekWspalsvesvllsiqsll..aepnpesplneeaa 123
           +++l +++ Ws+a++ve v+++i ++l   +++++ ++ +  +
   Q: 323  MELL-TKQGWSSAYTVEAVIMQIAATLvkGKARIQFGATKALT 364
           ****.59********************6656777777666554 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MACLNTLKQE IKTLEKIFPK NHERFQILNS SVDELLCRFI DKNGKRYDIH ANITETYPSS 60
PPVWFAESEE TSVTNAVQIL SNTNGRDNHV INQVGILLRE LCRLHNVPLP PDIDNLALPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTCATCGA TGACCAACGT ATCGCCATCC GTGGATCGCT AATTTGTTGT TGGTAAAAAA 60
AAGGTAAAGC GGGCGGGCGT GCGTGGAACA GAATTTAATT CTCCGTGTCA CAATTTTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0070936--P:protein K48-linked ubiquitination

KEGG

dme:Dmel_CG2924

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001442	Ailuropoda melanoleuca	53.01	2.00e-100	358.00
IUUC-Apl-003420	Anas platyrhynchos	53.58	6.00e-103	366.00
IUUC-Aca-004783	Anolis carolinensis	53.80	6.00e-46	175.00
IUUC-Afl-008523	Aspergillus flavus	28.10	9.00e-15	75.10
IUUC-Afu-009025	Aspergillus fumigatus	27.85	6.00e-15	75.90
IUUC-Ani-009397	Aspergillus nidulans	30.00	3.00e-11	63.50
IUUC-Ang-009729	Aspergillus niger	32.68	8.00e-19	89.00
IUUC-Aor-010200	Aspergillus oryzae	27.92	8.00e-15	75.50
IUUC-Ate-010283	Aspergillus terreus	28.33	3.00e-17	83.60
IUUC-Ame-011351	Astyanax mexicanus	50.76	2.00e-106	377.00
IUUC-Bta-012947	Bos taurus	49.15	2.00e-107	381.00
IUUC-Bci-013792	Botrytis cinerea	29.83	3.00e-17	83.60
IUUC-Cel-018705	Caenorhabditis elegans	46.12	2.00e-90	324.00
IUUC-Cja-019951	Callithrix jacchus	49.15	1.00e-107	382.00
IUUC-Cfa-020582	Canis familiaris	49.50	3.00e-109	387.00
IUUC-Cpo-022469	Cavia porcellus	51.36	3.00e-110	390.00
IUUC-Cre-022858	Chlamydomonas reinhardtii	32.85	3.00e-11	62.80
IUUC-Csa-023724	Chlorocebus sabaeus	51.62	2.00e-112	398.00
IUUC-Cho-024360	Choloepus hoffmanni	77.61	1.00e-59	221.00
IUUC-Cin-025383	Ciona intestinalis	44.39	2.00e-96	345.00
IUUC-Csv-025853	Ciona savignyi	35.96	3.00e-16	78.60
IUUC-Cgl-026471	Colletotrichum gloeosporioides	33.33	1.00e-18	88.60
IUUC-Dre-028429	Danio rerio	52.25	3.00e-108	384.00
IUUC-Dno-029771	Dasypus novemcinctus	51.86	2.00e-97	348.00
IUUC-Dor-030292	Dipodomys ordii	41.03	1.00e-61	229.00
IUUC-Dse-031418	Dothistroma septosporum	33.33	2.00e-16	81.30
IUUC-Ete-032744	Echinops telfairi	58.45	9.00e-44	169.00
IUUC-Eca-033376	Equus caballus	50.74	1.00e-111	395.00
IUUC-Eeu-034522	Erinaceus europaeus	48.67	2.00e-107	381.00
IUUC-Fca-036101	Felis catus	50.37	6.00e-109	386.00
IUUC-Fal-036837	Ficedula albicollis	49.64	2.00e-109	388.00
IUUC-Fox-038074	Fusarium oxysporum	29.53	4.00e-12	66.60
IUUC-Fso-038245	Fusarium solani	31.07	2.00e-16	80.90
IUUC-Gmo-039573	Gadus morhua	53.30	2.00e-114	404.00
IUUC-Ggr-039776	Gaeumannomyces graminis	31.03	3.00e-16	80.50
IUUC-Gga-041233	Gallus gallus	49.48	1.00e-101	362.00
IUUC-Gac-041518	Gasterosteus aculeatus	52.62	9.00e-115	405.00
IUUC-Ggo-044565	Gorilla gorilla	50.62	3.00e-108	384.00
IUUC-Hsa-046577	Homo sapiens	51.37	5.00e-110	390.00
IUUC-Itr-048119	Ictidomys tridecemlineatus	49.15	2.00e-107	381.00
IUUC-Lch-049417	Latimeria chalumnae	51.75	8.00e-115	405.00
IUUC-Loc-052754	Lepisosteus oculatus	53.92	2.00e-115	408.00
IUUC-Lma-052975	Leptosphaeria maculans	29.19	3.00e-20	93.60
IUUC-Laf-053736	Loxodonta africana	53.01	5.00e-100	357.00
IUUC-Mcc-055356	Macaca mulatta	49.15	2.00e-107	381.00
IUUC-Meu-056466	Macropus eugenii	72.38	2.00e-90	325.00
IUUC-Mor-057265	Magnaporthe oryzae	28.22	4.00e-10	60.10
IUUC-Mpo-057298	Magnaporthe poae	30.61	7.00e-14	72.80
IUUC-Mga-059200	Meleagris gallopavo	53.94	2.00e-101	361.00
IUUC-Mvi-060299	Microbotryum violaceum	41.75	2.00e-15	77.80
IUUC-Mmr-061213	Microcebus murinus	50.74	3.00e-111	394.00
IUUC-Mdo-062451	Monodelphis domestica	53.01	1.00e-100	358.00
IUUC-Mmu-063747	Mus musculus	49.63	2.00e-109	388.00
IUUC-Mpu-066198	Mustela putorius furo	50.49	5.00e-111	393.00
IUUC-Mlu-067549	Myotis lucifugus	49.16	2.00e-107	381.00
IUUC-Nfi-068376	Neosartorya fischeri	34.46	1.00e-13	71.60
IUUC-Nle-069221	Nomascus leucogenys	51.87	4.00e-113	400.00
IUUC-Opr-070331	Ochotona princeps	42.46	2.00e-71	261.00
IUUC-Ont-071632	Oreochromis niloticus	52.51	9.00e-115	405.00
IUUC-Oan-072781	Ornithorhynchus anatinus	56.49	1.00e-93	335.00
IUUC-Ocu-074097	Oryctolagus cuniculus	51.76	9.00e-112	395.00
IUUC-Ola-087271	Oryzias latipes	53.28	4.00e-116	410.00
IUUC-Olu-087612	Ostreococcus lucimarinus	29.41	3.00e-10	57.40
IUUC-Oga-089115	Otolemur garnettii	50.50	4.00e-111	393.00
IUUC-Oar-090270	Ovis aries	47.56	2.00e-107	381.00
IUUC-Ptr-090599	Pan troglodytes	51.37	1.00e-111	395.00
IUUC-Pan-092455	Papio anubis	51.62	2.00e-112	398.00
IUUC-Psi-093619	Pelodiscus sinensis	48.69	9.00e-85	305.00
IUUC-Pma-094631	Petromyzon marinus	74.15	3.00e-90	324.00
IUUC-Pno-095082	Phaeosphaeria nodorum	32.80	9.00e-15	75.50
IUUC-Ppa-095767	Physcomitrella patens	33.88	6.00e-16	79.30
IUUC-Pfo-096329	Poecilia formosa	53.40	2.00e-115	407.00
IUUC-Pab-098221	Pongo abelii	49.15	2.00e-107	381.00
IUUC-Pca-100506	Procavia capensis	39.85	5.00e-76	277.00
IUUC-Pva-103011	Pteropus vampyrus	47.85	5.00e-99	353.00
IUUC-Pte-104028	Pyrenophora teres	34.43	4.00e-17	83.60
IUUC-Pyt-104588	Pyrenophora triticirepentis	34.43	2.00e-16	81.30
IUUC-Rno-105296	Rattus norvegicus	49.15	1.00e-107	382.00
IUUC-Sha-106904	Sarcophilus harrisii	53.91	1.00e-101	362.00
IUUC-Ssl-108486	Sclerotinia sclerotiorum	33.89	2.00e-17	81.30
IUUC-Sar-113657	Sorex araneus	52.19	2.00e-98	350.00
IUUC-Ssc-115905	Sus scrofa	49.15	2.00e-107	381.00
IUUC-Tgu-116888	Taeniopygia guttata	53.94	2.00e-103	367.00
IUUC-Tru-118721	Takifugu rubripes	52.78	2.00e-115	407.00
IUUC-Tsy-118894	Tarsius syrichta	49.19	9.00e-72	262.00
IUUC-Tni-120346	Tetraodon nigroviridis	52.78	1.00e-114	405.00
IUUC-Tre-122084	Trichoderma reesei	29.28	3.00e-16	80.50
IUUC-Tvi-122420	Trichoderma virens	29.83	1.00e-13	72.00
IUUC-Tme-127145	Tuber melanosporum	37.16	3.00e-15	77.00
IUUC-Tbe-127490	Tupaia belangeri	52.75	9.00e-99	352.00
IUUC-Ttr-128707	Tursiops truncatus	50.74	9.00e-112	395.00
IUUC-Vda-129662	Verticillium dahliae	33.77	1.00e-12	68.20
IUUC-Vpa-130455	Vicugna pacos	53.04	4.00e-100	357.00
IUUC-Xtr-132483	Xenopus tropicalis	53.30	4.00e-116	410.00
IUUC-Xma-134189	Xiphophorus maculatus	53.65	9.00e-115	405.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence